ArticlePhysiology & behavior2008
Preferences of 14 rat strains for 17 taste compounds.
Article in Physiology & behavior, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed.
- Phenotypic Behavioural Effects of Genetic Deletion of the Vesicular Glutamate Transporter 3 in 5-Hydroxytryptamine Neurons.Genes, brain, and behavior · 2026Article
- Genetic Modulation of Oxycodone Self-Administration Trajectories: From Initiation to Escalating Burst Patterns.bioRxiv : the preprint server for biology · 2026Article
- Genetic modulation of oxycodone self-administration trajectories: from initiation to escalating burst patterns.Frontiers in behavioral neuroscience · 2026Article
- Sex differences in anxiety and depression: insights from adult rodent models of chronic stress and neural plasticity.Frontiers in behavioral neuroscience · 2025Review
- Short- and long-term changes in neurological, behavioural, and blood biomarkers following repeated mild traumatic brain injury in rats-potential biological sex-dependent effects.Frontiers in molecular neuroscience · 2025Article
- Re-evaluation of saccharin and its sodium, potassium and calcium salts (E 954) as food additives.EFSA journal. European Food Safety Authority · 2024Article
- The Effects of Fingolimod (FTY720) on Leukocyte Subset Circulation cannot be Behaviourally Conditioned in Rats.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2024Article
- The role of leukotriene inhibition using a 5-lipoxygenase (5-LO) inhibitor in a joint contracture model.Journal of experimental orthopaedics · 2023Article
- Red Quinoa Hydrolysates with Antioxidant Properties Improve Cardiovascular Health in Spontaneously Hypertensive Rats.Antioxidants (Basel, Switzerland) · 2023Article
- Sucrose Preference Test as a Measure of Anhedonic Behavior in a Chronic Unpredictable Mild Stress Model of Depression: Outstanding Issues.Brain sciences · 2022Review
- The sense of taste: Development, regeneration, and dysfunction.WIREs mechanisms of disease · 2022Review
- Sex differences in sucrose reinforcement in Long-Evans rats.Biology of sex differences · 2022Article
- Recovery of sweet taste preference in adult rats following bilateral chorda tympani nerve transection.PeerJ · 2022Article
- Genetic controls of Tas1r3-independent sucrose consumption in mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2021Article
- Enriched Environment Procedures for Rodents: Creating a Standardized Protocol for Diverse Enrichment to Improve Consistency across Research Studies.Bio-protocol · 2020Article
- Endogenous opioid dependence after intermittent use of glucose, sodium chloride, and monosodium glutamate solutions.Food science & nutrition · 2019Article
- Absence of compulsive drinking phenotype in adult male rats exposed to ethanol in a binge-like pattern during adolescence.Alcohol (Fayetteville, N.Y.) · 2019Article
- Exercise or saccharin during abstinence block estrus-induced increases in nicotine-seeking.Physiology & behavior · 2019Article
- Outcome-specific Pavlovian-to-instrumental transfer (PIT) with alcohol cues and its extinction.Alcohol (Fayetteville, N.Y.) · 2019Article
- Instrumental conditioning for food reinforcement in the spontaneously hypertensive rat model of attention deficit hyperactivity disorder.BMC research notes · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Two-bottle choice tests were used to assess the taste preferences of 8 male and 8 female rats from 3 outbred strains (SD, LE, WI) and 11 inbred strains (BN, BUF, COP, DA, Dahl-S, F344, FHH, LEW, Noble, PVG, SHR). Each rat received a series of 109 48-h tests with a choice between water and a "taste solution". Four to eight concentrations of the following compounds were tested: NaCl, CaCl2, NH4Cl, KCl, MgCl2, saccharin, sucrose, ethanol, HCl, citric acid, quinine hydrochloride (QHCl), caffeine, denatonium, monosodium glutamate (MSG), Polycose, corn oil, and capsaicin. Strain differences (p<0.001) were observed in preferences for at least one concentration of all compounds tested except denatonium (p=0.0015). There were also strain differences in the following ancillary measures: fungiform papillae number, water intake, food intake, and body weight. There were sex differences in food intake and body weight but no concerted sex differences in any of the other measures, including preferences for any taste solution. This comprehensive source of information can be used to guide the choice of appropriate rat strains and taste solution concentrations for future genetic studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.