Evidence map›Paper›PMID 18638068›Full record

ReviewJournal of anatomy2008

G1 to S phase cell cycle transition in somatic and embryonic stem cells.

Irina Neganova, Majlinda Lako

Open access · greenAbstract readReview
In one paragraph

Review in Journal of anatomy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 176 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. High Carbon Dioxide Concentration Inhibits Pileus Growth ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Coupling of stemness maintenance with cell cycle control in stem cells.Frontiers in cell and developmental biology · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Spatial-Temporal Genome Regulation in Stress-Response and Cell-Fate Change.International journal of molecular sciences · 2023
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Irina NeganovaNorth East Institute for Stem Cell Research, University of Newcastle upon Tyne, International Centre for Life, Newcastle NE1 3BZ, UK
Majlinda Lako
Centre for Life · GBNorth East University · BD

Funding

Biotechnology and Biological Sciences Research Council BB/E012841/1Biotechnology and Biological Sciences Research Council BBS/B/14779Medical Research Council G0301182
6 · The paper itself

Abstract

It is well known that G1 to S phase transition is tightly regulated by the expression and phosphorylation of a number of well-characterized cyclins, cyclin-dependent kinases and members of the retinoblastoma gene family. In this review we discuss the role of these components in regulation of G1 to S phase transition in somatic cells and human embryonic stem cells. Most importantly, we discuss some new tenable links between maintenance of pluripotency and cell cycle regulation in embryonic stem cells by describing the role that master transcription factors play in this process. Finally, the differences in cell cycle regulation between murine and human embryonic stem cells are highlighted, raising interesting questions regarding their biology and stages of embryonic development from which they have been derived.

Indexed as

G1 PhaseS PhaseAnimalsCell Cycle ProteinsEmbryonic Stem CellsHumansMicePhosphorylationPluripotent Stem CellsSpecies SpecificityTranscription FactorsCell Cycle ProteinsTranscription Factors

Identifiers

PMID18638068
PMCPMC2475562
OpenAlexW2088182309

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.