ArticleAddiction (Abingdon, England)2008
Relationship between white matter volume and cognitive performance during adolescence: effects of age, sex and risk for drug use.
Article in Addiction (Abingdon, England), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder.Nature. Mental health · 2025Article
- Article
- Neurobiological phenotypes associated with a family history of alcoholism.Drug and alcohol dependence · 2016Review
- Family history density of alcoholism relates to left nucleus accumbens volume in adolescent girls.Journal of studies on alcohol and drugs · 2015Article
- GABAergic contributions to alcohol responsivity during adolescence: insights from preclinical and clinical studies.Pharmacology & therapeutics · 2014Review
- Getting higher: co-occurring drug use among marijuana-using emerging adults.Journal of addictive diseases · 2014Article
- A triadic neurocognitive approach to addiction for clinical interventions.Frontiers in psychiatry · 2013Review
- VI. NIH Toolbox Cognition Battery (CB): measuring processing speed.Monographs of the Society for Research in Child Development · 2013Article
- Aerobic fitness relates to learning on a virtual Morris Water Task and hippocampal volume in adolescents.Behavioural brain research · 2012Article
- Atypical frontal lobe activity during verbal working memory in youth with a family history of alcoholism.Drug and alcohol dependence · 2012Article
- Risky decision-making: an FMRI study of youth at high risk for alcoholism.Alcoholism, clinical and experimental research · 2012Article
- Adolescents at risk for alcohol abuse demonstrate altered frontal lobe activation during Stroop performance.Alcoholism, clinical and experimental research · 2011Article
- Cognitive performance is related to cortical grey matter volumes in early stages of schizophrenia: a population-based study of first-episode psychosis.Schizophrenia research · 2009Article
- Adolescent brain development and underage drinking in the United States: identifying risks of alcohol use in college populations.Harvard review of psychiatryReview
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
aimFamilial drug abuse history has been shown to have an impact on cognitive development during adolescence. The present study examined the relationship between white matter volume and cognitive processing speed in adolescents with and without a familial substance abuse history.
participantsThe sample comprised 33 female and male adolescents stratified by risk (family history positive, FH+) and low-risk (FH-) groups. MEASUREMENTS: Gray and white matter volumes were measured by segmenting magnetic resonance imaging (MRI) data. The neurocognitive test battery included tests that assessed processing speed, verbal ability and mental flexibility.
findingsAge-related differences in neuropsychological functioning were seen but did not differ by risk group status, although there was some evidence for an age x gender effect. Information processing speed (digit symbol and Stroop word color naming) was correlated significantly with white matter volume; however, this pattern was observed only in FH- females. Cognitive performance and tissue volumes did not differ significantly between risk groups.
conclusionsAge-related differences in neuropsychological functioning were seen that might, in larger samples, prove to be related to risk for substance abuse in adolescents who have not yet initiated drug use.
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