Evidence map›Paper›PMID 18636317›Full record

ReviewMolecular and cellular biochemistry2008

Nutrigenomic basis of beneficial effects of chromium(III) on obesity and diabetes.

Francis C Lau, Manashi Bagchi, Chandan K Sen, Debasis Bagchi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular and cellular biochemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
  2. Impact of a food supplement containingFrontiers in nutrition · 2025
    Article
  3. Simultaneous binding characterization of different chromium speciation to serum albumin.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Antagonistic effects of nano-selenium on broilers hepatic injury induced by CrEnvironmental science and pollution research international · 2020
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Molecular mechanisms of chromium in alleviating insulin resistance.The Journal of nutritional biochemistry · 2012
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Francis C LauInterHealth Research Center, Benicia, CA, 94590, USA.
Manashi Bagchi
Chandan K Sen
Debasis Bagchi
PIH Health · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulin resistance has been shown to be the major contributing factor to the metabolic syndrome, which comprises a cluster of risk factors for metabolic aberrations such as obesity, dyslipidemia, hypertension, and hyperglycemia. Additionally, insulin resistance has been associated with the occurrence of cardiovascular disease and type 2 diabetes. Epidemiological studies indicate that obesity and diabetes have become alarmingly prevalent in recent years. Substantial evidence suggests that dietary interventions and regular exercise greatly improve body mass index and lipid profile as well as alleviate insulin resistance. Therefore, dietary supplements such as insulin-sensitizing agents may be beneficial in the prevention and treatment of obesity and type 2 diabetes. Numerous in vitro and in vivo studies suggest that chromium supplements, particularly niacin-bound chromium or chromium-nicotinate, may be effective in attenuating insulin resistance and lowering plasma cholesterol levels. Utilizing the powerful technology of nutrigenomics to identify the genes regulated by chromium supplementation may shed some light on the underlying mechanisms of chromium-gene interactions, and thus provide strategies to mitigate and prevent insulin-resistance-related disorders.

Indexed as

NutrigenomicsBiological AvailabilityChromiumDiabetes MellitusDietary SupplementsHumansObesityChromium

Identifiers

PMID18636317
OpenAlexW2147087645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.