Evidence map›Paper›PMID 18633421›Full record

Trial reportJournal of perinatology : official journal of the California Perinatal Association2008

Massage therapy reduces hospital stay and occurrence of late-onset sepsis in very preterm neonates.

E W Mendes, R S Procianoy

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03316547 (Supporting and Enhancing NICU Sensory Experiences to Optimize Developmental Outcomes in Preterm Infants), which is not on this map. Cited by 32 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 7 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03316547 nacompletednot on this mapstarted 2017, after this paper: background citation

Supporting and Enhancing NICU Sensory Experiences to Optimize Developmental Outcomes in Preterm Infants

TypeinterventionalSponsorWashington University School of MedicineRan2017 to 2019Enrolled70ConditionsPremature Birth of NewbornArmsSENSE Program
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 7 syntheses or guidelines pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Topical emollient for preventing infection in preterm infants.The Cochrane database of systematic reviews · 2021
    Pooled it
  7. Topical emollient for preventing infection in preterm infants.The Cochrane database of systematic reviews · 2016
    Pooled it
  8. Trial
  9. [Early rehabilitation intervention reduces the incidence of extrauterine growth retardation in preterm infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018
    Trial
  10. Trial
  11. A randomized-controlled trial pilot study examining the neurodevelopmental effects of a 5-week M Technique intervention on very preterm infants.Advances in neonatal care : official journal of the National Association of Neonatal Nurses · 2014
    Trial
  12. Trial
  13. Trial
  14. Article
  15. Article
  16. NICU sensory experiences associated with positive outcomes: an integrative review of evidence from 2015-2020.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Review
  17. Article
  18. Review
  19. The effect of sensory stimulation on apnea of prematurity.Journal of Taibah University Medical Sciences · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

E W MendesDepartment of Maternal-Infant Nursing, Nursing School, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
R S Procianoy
Hospital de Clínicas de Porto Alegre · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the effect of maternal massage therapy on hospital stay in very-low-birth-weight infants who were already submitted to skin-to-skin care. STUDY

designA randomized study was performed including infants of birth weight >or=750 and <or=1500 g and gestational age <or=32 weeks. The exclusion criteria were as follows: death before completing 48 h and presence of major malformations. Neonates were divided into intervention group (IG) (standard care plus maternal massage) and control group (CG). Anthropometric data were always verified by a person blind to the group to which the newborn belonged. Maternal massage was performed four times a day on the face and limbs. Passive exercises of upper and lower limbs were also done by the mothers.

resultA total of 104 newborns were included, 52 in each group. Both groups were similar in gestational age (IG: 29.7+/-1.6; CG: 29.4+/-1.6 weeks), birth weight (IG: 1186+/-194; CG: 1156+/-198 g), gender, number of small-for-gestational-age infants, SNAPPE-II, deaths, gains in weight, length and head circumference. Incidence of late-onset sepsis was significantly lower in the intervention group (IG: 10.8%, n=5; CG: 38.3%, n=18; P=0.005). IG was discharged from the hospital 7 days before CG (IG: 42, confidence interval (CI) 95%: 38 to 46; CG: 49, CI 95%: 42 to 56), and presented 1.85 hazard ratio (CI 95%: 1.09 to 3.13; P=0.023) for early discharge.

conclusionMaternal massage therapy in very-low-birth-weight infants decreases the length of hospital stay and the incidence of late-onset neonatal sepsis.

Indexed as

MassageAge of OnsetFemaleGestational AgeHumansInfant, NewbornInfant, Very Low Birth WeightLength of StayMalePremature BirthSepsisTime Factors

Identifiers

PMID18633421
OpenAlexW2065304752

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.