Trial reportJournal of perinatology : official journal of the California Perinatal Association2008
Effects of motor physical therapy on bone mineralization in premature infants: a randomized controlled study.
Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Self Regulated Physical Activity and Bone Growth Enhancement in Premature Infants
Effect of Physiotherapy on the Promotion of Bone Mineralization in Preterm Infants
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Prevention and management of metabolic bone disease of prematurity: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2026Pooled it
- Physical activity programs for promoting bone mineralization and growth in preterm infants.The Cochrane database of systematic reviews · 2014Pooled it
- Effect of physiotherapy on the promotion of bone mineralization in preterm infants: a randomized controlled trial.Scientific reports · 2022Trial
- Effect of physical therapy on bone remodelling in preterm infants: a multicenter randomized controlled clinical trial.BMC pediatrics · 2022Trial
- Interventions for metabolic bone disease of prematurity: A systematic review and meta-analysis.Metabolism open · 2026Article
- L'évaluation et l'optimisation de la santé osseuse chez les enfants ayant des affections chroniques.Paediatrics & child health · 2022Article
- Evaluating and optimizing bone health in children with chronic health conditions.Paediatrics & child health · 2022Article
- The impact of an early intervention home-based program on body composition in preterm-born preschoolers with very low birth weight.Frontiers in nutrition · 2022Article
- Physical Therapy to Prevent Osteopenia in Preterm Infants: A Systematic Review.Children (Basel, Switzerland) · 2021Review
- Breech presentation is associated with lower adolescent tibial bone strength.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Article
- Effect of Early Physical Activity Programs on Motor Performance and Neuromuscular Development in Infants Born Preterm: A Randomized Clinical Trial.Journal of caring sciences · 2017Article
- Increasing F2-isoprostanes in the first month after birth predicts poor respiratory and neurodevelopmental outcomes in very preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2016Observational
- Short-Term Effects of Hydrokinesiotherapy in Hospitalized Preterm Newborns.Rehabilitation research and practice · 2016Article
- Daily physical activity in low-risk extremely low birth weight preterm infants: positive impact on bone mineral density and anthropometric measurements.Journal of bone and mineral metabolism · 2015Article
- Feasibility of a caregiver-assisted exercise program for preterm infants.The Journal of perinatal & neonatal nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study the effect of physical therapy on bone mineralization, weight gain and growth in preterm infants.
methodAfter fulfilling the inclusion criteria, preterm infants were matched for gestational age and birth weight and then randomly assigned to the physiotherapy group (PG, n=15) and control group (CG, n=14). The PG received motor physical therapy for 15 min daily, 5 times per week until hospital discharge. Bone mineralization was measured by total body dual energy X-ray beam absorptiometry (DEXA) at the onset and end of the study. Statistical analysis was realized by ANCOVA and linear correlation tests.
resultThe physical therapy group (PG) presented greater body weight gain per day (27.4+/-2.4 vs 21.01+/-4.4 g, P<0.001) and length (1.3+/-0.3 vs 0.8+/-0.2 cm week(-1), P<0.001) than did the control group (CG). Body composition values verified by DEXA were greater for the PG. The mean gain in bone mineral content (BMC) (mg) was greater in the PG (434+/-247.5 vs -8.9+/-11.4, P<0.001), as was the mean bone mineral density (BMD) gain (mg cm(-2)) (8.4+/-5.6 vs -3.1+/-5.5, P<0.001). The gain in bone area (BA,cm(2)) was 10.3+/-5 in the PG vs 1.5 +/-2 in the CG (P<0.001). The gain in lean mass (LM) (g) in the PG was also greater than in the CG (271.1+/-21.4 vs 109.1+/-1.0, P<0.009). The fat mass (g) was similar between the groups (P=0.432).
conclusionThese results showed that physiotherapy in preterm infants produced greater gains in growth, body weight, BMC, BMD, BA and LM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.