Evidence map›Paper›PMID 18632907›Full record

ArticleJournal of clinical microbiology2008

Trends in species distribution and susceptibility of bloodstream isolates of Candida collected in Monterrey, Mexico, to seven antifungal agents: results of a 3-year (2004 to 2007) surveillance study.

Gloria M González, Mariana Elizondo, Jacobo Ayala

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Species-specific antifungal resistance trends in yeast bloodstream isolates causing candidemia before, during, and after the COVID-19 pandemic: insights from the INVIFAR Mexican multicenter network.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Prevalence and Species Distribution ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  6. Clinics and practice · 2024
    Article
  7. Meyerozyma guilliermondii species complex: review of current epidemiology, antifungal resistance, and mechanisms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Review
  8. Article
  9. Article
  10. Review
  11. Active Flavonoids fromMolecules (Basel, Switzerland) · 2021
    Article
  12. Epidemiology, risk factors and outcomes ofEpidemiology and infection · 2019
    Article
  13. Article
  14. Article
  15. Observational
  16. Article
  17. Review
  18. Efficacy and safety of itraconazole use in infants.World journal of pediatrics : WJP · 2016
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gloria M GonzálezDepartamento de Microbiología, Facultad de Medicina, Universidad Autónoma de Nuevo León, Colonia Mitras Centro, Monterrey, NL, México. gmglez@yahoo.com.mx
Mariana Elizondo
Jacobo Ayala

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During a 3-year surveillance program (2004 to 2007) in Monterrey, Mexico, 398 isolates of Candida spp. were collected from five hospitals. We established the species distribution and in vitro susceptibilities of these isolates. The species included 127 Candida albicans strains, 151 C. parapsilosis strains, 59 C. tropicalis strains, 32 C. glabrata strains, 11 C. krusei strains, 5 C. guilliermondii strains, 4 C. famata strains, 2 C. utilis strains, 2 C. zeylanoides strains, 2 C. rugosa strains, 2 C. lusitaniae strains, and 1 C. boidinii strain. The species distribution differed with the age of the patients. The proportion of candidemias caused by C. parapsilosis was higher among infants <or=1 year old, and the proportion of candidemias caused by C. glabrata increased with patient age (>45 years old). MICs were calculated following the criteria of the Clinical Laboratory Standards Institute reference broth macrodilution method. Overall, C. albicans, C. parapsilosis, and C. tropicalis isolates were susceptible to fluconazole and amphotericin B. However, 31.3% of C. glabrata isolates were resistant to fluconazole (MIC >or= 64 microg/ml), 43.3% were resistant to itraconazole (MIC >or= 1 microg/ml), and 12.5% displayed resistance to amphotericin B (MIC >or= 2 microg/ml). Newer triazoles, namely, voriconazole, posaconazole, and ravuconazole, had a notable in vitro activity against all Candida species tested. Also, caspofungin was active against Candida sp. isolates (MIC(90) <or= 0.5 microg/ml) except C. parapsilosis (MIC(90) = 2 microg/ml). It is imperative to promote a national-level surveillance program to monitor this important microorganism.

Indexed as

AdolescentAdultAgedAged, 80 and overAge FactorsAmphotericin BAntifungal AgentsCandidaCandida albicansCandida glabrataCandida tropicalisCandidiasisCaspofunginChildChild, PreschoolEchinocandinsAmphotericin BAntifungal AgentsCaspofunginEchinocandinsER 30346FluconazoleItraconazoleLipopeptidesposaconazolePyrimidinesThiazolesTriazolesVoriconazole

Identifiers

PMID18632907
PMCPMC2546732

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.