Evidence map›Paper›PMID 18631973›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2008

Commentary on "Perspective on race and ethnicity in Alzheimer's disease research".

Derek M Griffith, Patrick A Griffith

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Ethnicity, nativity, and the health of American Blacks.Journal of health care for the poor and underserved · 2011
    Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Derek M GriffithDepartment of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, MI, USA. pgriffith@mmc.edu
Patrick A Griffith
Meharry Medical College · USMichigan Department of Health and Human Services · US

Funding

WYETH 303 STUDYP20RR011792 · NCRR · MEHARRY MEDICAL COLLEGE · PI MONTGOMERY-RICE, VALERIE C. · 1996 to 2009
$14.4M
NCRR NIH HHS P20RR011792
6 · The paper itself

Abstract

There are persistent disparities in Alzheimer's disease by race and ethnicity that are not well understood. The emphasis given to seeking a genetic basis for racial differences might be a distraction from the more relevant issue of identifying preventable causes of Alzheimer's disease. The majority of Alzheimer's disease cases are diagnosed as the late onset type and are unlikely to be inherited. Late onset Alzheimer's disease cases, therefore, more likely represent variations in gene expression than gene frequency. Although conceptual and methodologic problems have limited our understanding of this relationship, race-based studies provide important opportunities to understand the environmental factors associated with gene expression. Improving our understanding of the factors associated with race and ethnicity might help to clarify the epidemiology and course of Alzheimer's disease.

Indexed as

EthnicityRacial GroupsAlzheimer DiseaseGene ExpressionHumansRisk Factors

Identifiers

PMID18631973
OpenAlexW2057347139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.