Evidence map›Paper›PMID 18631387›Full record

ReviewJournal of experimental & clinical cancer research : CR2008

Non-protein coding RNA biomarkers and differential expression in cancers: a review.

Massimo Mallardo, Palmiro Poltronieri, Oscar Fernando D'Urso

Open access · goldAbstract readReview
In one paragraph

Review in Journal of experimental & clinical cancer research : CR, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 61 citations in OpenAlex.

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  13. In vitro antineoplastic effects of brivaracetam and lacosamide on human glioma cells.Journal of experimental & clinical cancer research : CR · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Massimo MallardoUniversity of Napoli Federico II, Department of Biochemistry and Medical Biotechnologies, Via S, Pansini 5, Napoli, Italy. mallardo@dbbm.unina.it
Palmiro Poltronieri
Oscar Fernando D'Urso
Federico II University Hospital · ITInstitute of Sciences of Food Production · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn these years a huge number of human transcripts has been found that do not code for proteins, named non-protein coding RNAs. In most cases, small (miRNAs, snoRNAs) and long RNAs (antisense RNA, dsRNA, and long RNA species) have many roles, functioning as regulators of other mRNAs, at transcriptional and post-transcriptional level, and controlling protein ubiquitination and degradation. Various species of npcRNAs have been found differentially expressed in different types of cancer. This review discusses the published data and new results on the expression of a subset of npcRNAs.

conclusionThese results underscore the complexity of the RNA world and provide further evidence on the involvement of functional RNAs in cancer cell growth control.

Indexed as

AnimalsBiomarkers, TumorCell Transformation, NeoplasticGene ExpressionHumansMicroRNAsNeoplasmsRNA, AntisenseRNA, UntranslatedBiomarkers, TumorMicroRNAsRNA, AntisenseRNA, Untranslated

Identifiers

PMID18631387
PMCPMC2490676
OpenAlexW2154627535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.