Evidence map›Paper›PMID 18629844›Full record

ArticleCytometry. Part A : the journal of the International Society for Analytical Cytology2008

Polychromatic plots: graphical display of multidimensional data.

Mario Roederer, M Anthony Moody

Abstract read
In one paragraph

Article in Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. SPICE: exploration and analysis of post-cytometric complex multivariate datasets.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2011
    Article
  5. Article
  6. Publishing flow cytometry data.American journal of physiology. Lung cellular and molecular physiology · 2010
    Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Mario RoedererVaccine Research Center, NIH, Bethesda, Maryland 20892-3015, USA. Roederer@nih.gov
M Anthony Moody

Funding

Flow Cytometry CoreZICAI005101 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ROEDERER, MARIO · 2009 to 2025
$25.7M
Develop Of Flow Cytometric Technologies For Immune AssayZ01AI005020 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI ROEDERER, MARIO · 2002 to 2008
$1.4M
Intramural NIH HHS Z01 AI005020
6 · The paper itself

Abstract

Limitations of graphical displays as well as human perception make the presentation and analysis of multidimensional data challenging. Graphical display of information on paper or by current projectors is perforce limited to two dimensions; the encoding of information from other dimensions must be overloaded into the two physical dimensions. A number of alternative means of encoding this information have been implemented, such as offsetting data points at an angle (e.g., three-dimensional projections onto a two-dimensional surface) or generating derived parameters that are combinations of other variables (e.g., principal components). Here, we explore the use of color to encode additional dimensions of data. PolyChromatic Plots are standard dot plots, where the color of each event is defined by the values of one, two, or three of the measurements for that event. The measurements for these parameters are mapped onto an intensity value for each primary color (red, green, or blue) based on different functions. In addition, differential weighting of the priority with which overlapping events are displayed can be defined by these same measurements. PolyChromatic Plots can encode up to five independent dimensions of data in a single display. By altering the color mapping function and the priority function, very different displays that highlight or de-emphasize populations of events can be generated. As for standard black-and-white dot plots, frequency information can be significantly biased by this display; care must be taken to ensure appropriate interpretation of the displays. PolyChromatic Plots are a powerful display type that enables rapid data exploration. By virtue of encoding as many as five dimensions of data independently, an enormous amount of information can be gleaned from the displays. In many ways, the display performs somewhat like an unsupervised cluster algorithm, by highlighting events of similar distributions in multivariate space.

Indexed as

Flow CytometryCD4-Positive T-LymphocytesCells, CulturedColorComputer GraphicsEnterotoxinsHumansSuperantigensenterotoxin B, staphylococcalEnterotoxinsSuperantigens

Identifiers

PMID18629844
PMCPMC2583940

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.