Evidence map›Paper›PMID 18627655›Full record

ReviewCurrent gastroenterology reports2008

Gastrointestinal cytomegalovirus disease in the immunocompromised patient.

Allison L Baroco, Edward C Oldfield

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 101 citations in OpenAlex.

  1. A machine learning model for accurate prediction of CMV end-organ disease.BMC medical informatics and decision making · 2026
    Article
  2. Article
  3. Analysis of Cytomegalovirus Infection Affecting the Stomach.Gastroenterology research and practice · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Pathogens (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Immune surveillance of cytomegalovirus in tissues.Cellular & molecular immunology · 2024
    Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Gastrointestinal complications after kidney transplantation.World journal of gastroenterology · 2020
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Allison L BarocoEastern Virginia Medical School, Department of Internal Medicine, Division of Infectious Diseases, 825 Fairfax Avenue, Suite 410, Norfolk, VA 23507, USA. barocoal@evms.edu
Edward C Oldfield
Eastern Virginia Medical School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus (CMV) has emerged as a significant opportunistic pathogen in the era of immunosuppression. CMV was a common cause of gastrointestinal disease in AIDS patients, but the introduction of highly active antiretroviral therapy has led to a dramatic decline in AIDS-related disease. Among patients with solid organ transplants, CMV has become an increasingly important cause of gastrointestinal disease as more routine use of early CMV prophylaxis has increased delayed-onset disease, which is often tissue invasive at presentation. The role of CMV in inflammatory bowel disease is controversial; treatment may be indicated in selected cases of steroid-refractory disease with evidence of CMV. Diagnosis of gastrointestinal CMV disease generally requires endoscopic biopsy with histologic confirmation. CMV culture of biopsy material may be falsely positive because of contamination from latently infected cells. The standard induction treatment of gastrointestinal CMV disease uses intravenous ganciclovir, though the use of oral valganciclovir is increasing, especially for long-term maintenance or suppression therapy.

Indexed as

Cytomegalovirus InfectionsImmunocompromised HostAIDS-Related Opportunistic InfectionsAntiviral AgentsEsophagitisGanciclovirGastrointestinal DiseasesHumansInflammatory Bowel DiseasesNeoplasmsOpportunistic InfectionsOrgan TransplantationAntiviral AgentsGanciclovir

Identifiers

PMID18627655
OpenAlexW2008918520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.