ArticleBMC infectious diseases2008
Use of multiple methods for genotyping Fusarium during an outbreak of contact lens associated fungal keratitis in Singapore.
Article in BMC infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 16 citations in OpenAlex.
- Novel amplified fragment length polymorphism (AFLP) markers for typing medically relevantFungal systematics and evolution · 2025Article
- Disinfectants in a Hemodialysis Setting: Antifungal Activity AgainstFrontiers in cellular and infection microbiology · 2021Article
- A 23 bpFrontiers in microbiology · 2020Article
- Investigating Clinical Issues by Genotyping of Medically Important Fungi: Why and How?Clinical microbiology reviews · 2017Review
- Fusarium napiforme systemic infection: case report with molecular characterization and antifungal susceptibility tests.SpringerPlus · 2014Article
- Diagnosis ofCurrent fungal infection reportsReview
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Singapore, an outbreak of fungal keratitis caused by members of the Fusarium solani species complex (FSSC) was identified in March 2005 to May 2006 involving 66 patients. Epidemiological investigations have indicated that improper contact lens wear and the use of specific contact lens solutions were risk factors.
methodsWe assessed the genetic diversity of the isolates using AFLP, Rep-PCR, and ERIC-PCR and compared the usefulness of these typing schemes to characterize the isolates.
resultsAFLP was the most discriminative typing scheme and appears to group FSSC from eye infections and from other infections differently.
conclusionThere was a high genomic heterogeneity among the isolates confirming that this was not a point source outbreak.
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Registered trials
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