Trial reportLangenbeck's archives of surgery2008
The use of "harmonic scalpel" versus "knot tying" for conventional "open" thyroidectomy: results of a prospective randomized study.
Trial report in Langenbeck's archives of surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- High-energy devices in different surgical settings: lessons learnt from a full health technology assessment report developed by SICE (Società Italiana di Chirurgia Endoscopica).Surgical endoscopy · 2023Pooled it
- The role of LigaSure™ and Harmonic Scalpel in the preservation of recurrent laryngeal nerve during thyroidectomy.Annals of the Royal College of Surgeons of England · 2022Pooled it
- Energy Based Vessel Sealing Devices in Thyroid Surgery: A Systematic Review to Clarify the Relationship with Recurrent Laryngeal Nerve Injuries.Medicina (Kaunas, Lithuania) · 2020Pooled it
- ENERgized vessel sealing systems versus CONventional hemostasis techniques in thyroid surgery--the ENERCON systematic review and network meta-analysis.Langenbeck's archives of surgery · 2013Pooled it
- Meta-analysis of thyroidectomy with ultrasonic dissector versus conventional clamp and tie.World journal of surgical oncology · 2010Pooled it
- Use of ultrasonic scalpel and monopolar electrocautery for skin incisions in neck dissection: a prospective randomized trial.Oral and maxillofacial surgery · 2018Trial
- Sutureless thyroidectomy with energy-based devices: Cerrahpasa experience.Updates in surgery · 2013Trial
- Harmonic scalpel versus conventional haemostasis in neck dissection: a prospective randomized study.International journal of surgical oncology · 2013Trial
- Harmonic Focus™ versus "knot tying" during total thyroidectomy: a randomized trial.Updates in surgery · 2011Trial
- Harmonic focus in total thyroidectomy plus level III-IV and VI dissection: a prospective randomized study.World journal of surgical oncology · 2011Trial
- Update on sutureless thyroidectomy.Il Giornale di chirurgiaTrial
- Tension-free thyroidectomy (TFT): initial report.Updates in surgery · 2022Article
- Association of Vessel-Sealant Devices vs Conventional Hemostasis With Postoperative Neck Hematoma After Thyroid Operations.JAMA surgery · 2019Observational
- Procedure costs associated with the use of Harmonic devices compared to conventional techniques in various surgeries: a systematic review and meta-analysis.ClinicoEconomics and outcomes research : CEOR · 2018Review
- A comparison of surgical outcomes and complications between hemostatic devices for thyroid surgery: a network meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017Review
- Article
- Article
- The comparison of the harmonic focus shears device with conventional clamp binding in total thyroidectomy.International journal of clinical and experimental medicine · 2015Article
- The impact of the Harmonic FOCUS™ on complications in thyroid surgery: a prospective multicenter study.Updates in surgery · 2013Article
- Total thyroidectomy for non-toxic multinodular goiter with versus without the use of harmonic FOCUS dissecting shears - a prospective randomized study.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2012Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe evaluated the safety and cost-effectiveness of the harmonic scalpel (HS) during conventional "open" thyroidectomy (CT). MATERIALS AND
methodsTwo hundred patients scheduled for conventional total thyroidectomy (TT) were included in the study and randomly assigned to TT with the use of HS (HS group) or with knot tying technique (KT group).
resultsMean operative time was significantly shorter in the HS group (P < 0.001), as well as the total operative room occupation time (P < 0.001). The cost of the disposable materials is significantly higher in the HS group (420.1 +/- 23.2 vs 137.8 +/- 25.3 euros; P < 0.001). Conversely, drugs, personnel and operative room charges were significantly higher in KT group patients (P < 0.001). Overall, no significant difference was found between the two groups concerning the charges of the hospitalisation (P = NS).
conclusionsHS is a safe alternative to KT, allowing for a significant reduction of operative time without increasing complications rate and overall costs and probably better utilization of health resources.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.