ArticleImmunogenetics2008
MHC haplotype involvement in avian resistance to an ectoparasite.
Article in Immunogenetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 62 citations in OpenAlex.
- The relationship between infestation level and the welfare of cage-free laying hens experimentally infested with northern fowl mites.Poultry science · 2026Article
- Genetic characterization of the TAPBP and its allelic association with BF2 in the chicken major histocompatibility complex.Immunogenetics · 2026Article
- Identification and comparative analysis of novel major histocompatibility complex-B haplotypes in Indonesian native chickens.Animal bioscience · 2026Article
- Host genetics, lung T-cell immunity, and laying activity determine the disease outcome in avian influenza virus-infected chickens.Veterinary research · 2026Article
- Identification of new major histocompatibility complex-B haplotypes in chinese broilers.Poultry science · 2025Article
- The MHC (Major Histocmpatibility Complex) Exceptional Molecules of Birds and Their Relationship to Diseases.International journal of molecular sciences · 2025Review
- MHC-linked microsatellite LEI0258 variability and population structure of chicken ecotypes in Iran.Iranian journal of veterinary research · 2025Article
- Discovery of novel MHC-B haplotypes in Chantecler chickens.Poultry science · 2023Article
- Factors associated with prevalence and intensity of the northern fowl mite (Ornithonyssus sylviarum) in commercial poultry farms of Argentina.Parasitology research · 2022Article
- The Chicken MHC: Insights into Genetic Resistance, Immunity, and Inflammation Following Infectious Bronchitis Virus Infections.Vaccines · 2020Review
- Major histocompatibility complex B variability in Korean native chicken breeds.Poultry science · 2020Article
- Assessing MHC-B diversity in Silkie chickens.Poultry science · 2020Article
- Association between louse abundance and MHC II supertypes in Galápagos mockingbirds.Parasitology research · 2020Article
- Advances in methodologies for detecting MHC-B variability in chickens.Poultry science · 2020Review
- Genetic diversity at major histocompatibility complex and its effect on production and immune traits in indigenous chicken breeds of India.Archives animal breeding · 2020Article
- Field evaluation of poultry red mite (Dermanyssus gallinae) native and recombinant prototype vaccines.Veterinary parasitology · 2017Article
- Brief review of the chicken Major Histocompatibility Complex: the genes, their distribution on chromosome 16, and their contributions to disease resistance.Poultry science · 2016Review
- A high-density SNP panel reveals extensive diversity, frequent recombination and multiple recombination hotspots within the chicken major histocompatibility complex B region between BG2 and CD1A1.Genetics, selection, evolution : GSE · 2016Article
- Salmonella enterica Serovars Enteritidis Infection Alters the Indigenous Microbiota Diversity in Young Layer Chicks.Frontiers in veterinary science · 2015Article
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Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research on immune function in evolutionary ecology has frequently focused on avian ectoparasites (e.g., mites and lice). However, host immunogenetics involved with bird resistance to ectoparasites has not been determined. The critical role of the major histocompatibility complex (MHC) in adaptive immunity and high genetic variation found within the MHC make this gene complex useful for exploring the immunogenetic basis for bird resistance to ectoparasites. The objective of this study was to determine if the avian MHC influenced resistance to a blood-feeding ectoparasite. Four congenic lines of chickens, differing only at the MHC, were comparatively infested with a cosmopolitan ectoparasite of birds-northern fowl mite (NFM)-which is also a serious pest species of poultry. Mite infestations were monitored over time and mite densities (weekly and maximum) were compared among lines. Chickens with the MHC haplotype B21 were relatively resistant to NFM, compared with birds in the B15 congenic line (P < 0.02). To test for similar effects in an outbred genetic background, a separate experiment was performed with 107 commercial chickens (white leghorn, W-36 strain) infested with NFM. Hens were genotyped using a MHC microsatellite marker (LEI0258) and associations between MHC haplotype and NFM density were tested. The highest peak NFM populations occurred more often on hens with the B15 haplotype versus the B21 haplotype (P = 0.012), which supported the results of the congenic study. These data indicate the avian MHC influences ectoparasite resistance, which is relevant to disease ecology and avian-ectoparasite interaction.
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