ArticleLearning & memory (Cold Spring Harbor, N.Y.)2008
Facilitation of taste memory acquisition by experiencing previous novel taste is protein-synthesis dependent.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 57 citations in OpenAlex.
- Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice.The Journal of clinical investigation · 2023Article
- Effects of exploring a novel environment on memory across the lifespan.Scientific reports · 2022Article
- Differential Recruitment of the Infralimbic Cortex in Recent and Remote Retrieval and Extinction of Aversive Memory in Post-Weanling Rats.The international journal of neuropsychopharmacology · 2022Article
- Cortical taste processing evolves through benign taste exposures.Behavioral neuroscience · 2022Article
- Neuropsin-dependent and -independent behavioral tagging.Neuropsychopharmacology reports · 2021Article
- Dopamine-Dependent QR2 Pathway Activation in CA1 Interneurons Enhances Novel Memory Formation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Taste Processing: Insights from Animal Models.Molecules (Basel, Switzerland) · 2020Review
- The role of the gustatory cortex in incidental experience-evoked enhancement of later taste learning.Learning & memory (Cold Spring Harbor, N.Y.) · 2018Article
- Novelty enhances memory persistence and remediates propranolol-induced deficit via reconsolidation.Neuropharmacology · 2018Article
- Locus Coeruleus and Dopamine-Dependent Memory Consolidation.Neural plasticity · 2017Review
- The Insula and Taste Learning.Frontiers in molecular neuroscience · 2017Review
- Preexposure to salty and sour taste enhances conditioned taste aversion to novel sucrose.Learning & memory (Cold Spring Harbor, N.Y.) · 2016Article
- Fluid consumption and taste novelty determines transcription temporal dynamics in the gustatory cortex.Molecular brain · 2016Article
- Expression of Quinone Reductase-2 in the Cortex Is a Muscarinic Acetylcholine Receptor-Dependent Memory Consolidation Constraint.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- A molecular mechanism underlying gustatory memory trace for an association in the insular cortex.eLife · 2015Article
- Behavioral Tagging: A Translation of the Synaptic Tagging and Capture Hypothesis.Neural plasticity · 2015Review
- Genetic or pharmacological reduction of PERK enhances cortical-dependent taste learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Neonatal representation of odour objects: distinct memories of the whole and its parts.Proceedings. Biological sciences · 2014Article
- Article
- The synaptic plasticity and memory hypothesis: encoding, storage and persistence.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Very little is known about the biological and molecular mechanisms that determine the effect of previous experience on implicit learning tasks. In the present study, we first defined weak and strong taste inputs according to measurements in the behavioral paradigm known as latent inhibition of conditioned taste aversion. We then demonstrated that a strong novel taste input facilitated acquisition of the memory of subsequent weak taste input in inverse correlation with the time interval between the inputs. However, not only was a strong taste input unable to rescue an immediately subsequent strong taste input when the gustatory cortex was under the influence of the protein-synthesis inhibitor, anisomycin, but the effect of the interaction was to reduce the variation among individual taste memories. Taken together, these results demonstrate that taste memory facilitation, induced by previously experiencing a different unimodal taste input, depended on time, novelty, and directionality. Moreover, the results imply that learning is enhanced on the level of acquisition but not of molecular consolidation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.