Evidence map›Paper›PMID 18625770›Full record

ArticleAntimicrobial agents and chemotherapy2008

Recombination and selection can remove blaTEM alleles from bacterial populations.

Joanna E Mroczkowska, Miriam Barlow

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Presence of bla TEM-116 Gene in Environmental Isolates of Aeromonas Hydrophila and Aeromonas Jandaei from Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joanna E MroczkowskaSchool of Natural Sciences, University of California, Merced, 5200 North Lake Road, Merced, California 95343, USA.
Miriam Barlow

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We passaged cells expressing TEM-1 and TEM-12 from a single plasmid through either ampicillin or ceftazidime. We found that the combined effects of recombination and selection removed the bla(TEM-1) allele from the bacterial population when it was passaged through ceftazidime or the bla(TEM-12) allele when cultures were passaged through ampicillin.

Indexed as

AllelesRecombination, GeneticSelection, GeneticAmpicillinAnti-Bacterial Agentsbeta-LactamasesCeftazidimeCulture MediaEscherichia coli K12AmpicillinAnti-Bacterial Agentsbeta-Lactamasesbeta-lactamase TEM-1beta-lactamase TEM-12CeftazidimeCulture Media

Identifiers

PMID18625770
PMCPMC2533445

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.