Evidence map›Paper›PMID 18625598›Full record

ArticleBMJ (Clinical research ed.)2008

A model based on age, sex, and morbidity to explain variation in UK general practice prescribing: cohort study.

Rumana Z Omar, Caoimhe O'Sullivan, Irene Petersen, Amir Islam, Azeem Majeed

Abstract readMulticenter Study
In one paragraph

Article in BMJ (Clinical research ed.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Observational
  2. Visualizing nationwide variation in medicare Part D prescribing patterns.BMC medical informatics and decision making · 2018
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Adverse events recorded in English primary care: observational study using the General Practice Research Database.The British journal of general practice : the journal of the Royal College of General Practitioners · 2013
    Observational
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rumana Z OmarDepartment of Statistical Science, University College London, London WC1E 6BT. rumana@stats.ucl.ac.uk
Caoimhe O'Sullivan
Irene Petersen
Amir Islam
Azeem Majeed

Funding

Department of HealthMedical Research Council G0601726
6 · The paper itself

Abstract

objectiveTo examine whether patient level morbidity based measure of clinical case mix explains variations in prescribing in general practice.

designRetrospective study of a cohort of patients followed for one year.

settingUK General Practice Research Database.

participants129 general practices, with a total list size of 1 032 072.

main outcome measuresEach patient was assigned a morbidity group on the bases of diagnoses, age, and sex using the Johns Hopkins adjusted clinical group case mix system. Multilevel regression models were used to explain variability in prescribing, with age, sex, and morbidity as predictors.

resultsThe median number of prescriptions issued annually to a patient is 2 (90% range 0 to 18). The number of prescriptions issued to a patient increases with age and morbidity. Age and sex explained only 10% of the total variation in prescribing compared with 80% after including morbidity. When variation in prescribing was split between practices and within practices, most of the variation was at the practice level. Morbidity explained both variations well.

conclusionsInclusion of a diagnosis based patient morbidity measure in prescribing models can explain a large amount of variability, both between practices and within practices. The use of patient based case mix systems may prove useful in allocation of budgets and therefore should be investigated further when examining prescribing patterns in general practices in the UK, particularly for specific therapeutic areas.

Indexed as

AdolescentAdultAgedAge DistributionChildChild, PreschoolCohort StudiesFamily PracticeFemaleHumansInfantMaleMiddle AgedMorbidityPractice Patterns, Physicians'Regression Analysis

Identifiers

PMID18625598
PMCPMC2658517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.