ReviewCurrent hypertension reports2008
Advances in the understanding of eclampsia.
Review in Current hypertension reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- The diagnosis and treatment of hypertensive disorders of pregnancy: new findings for antenatal and inpatient care.Deutsches Arzteblatt international · 2009Pooled it
- Differential regulation of a placental SAM68 and sFLT1 gene pathway and the relevance to maternal vitamin D sufficiency.Pregnancy hypertension · 2020Trial
- Complications and outcome of atypical preeclampsia, and eclampsia, at al Saudi Hospital, Sudan.BMC pregnancy and childbirth · 2025Article
- History of hypertensive disorders of pregnancy and risk of Alzheimer's disease and vascular dementia.Frontiers in neuroendocrinology · 2025Review
- Review
- Therapeutic potential of extracellular vesicles for treating human pregnancy disorders.Extracellular vesicles and circulating nucleic acids · 2025Review
- Preeclampsia and eclampsia: the conceptual evolution of a syndrome.American journal of obstetrics and gynecology · 2022Review
- Not all is COVID19: a case of eclampsia and posterior reversible encephalopathy syndrome in the emergency room.Acta bio-medica : Atenei Parmensis · 2021Article
- Mechanotransduction and Uterine Blood Flow in Preeclampsia: The Role of Mechanosensing Piezo 1 Ion Channels.American journal of hypertension · 2020Review
- Bronchopulmonary dysplasia: Pathogenesis and treatment.Experimental and therapeutic medicine · 2018Review
- Antibody to Marinobufagenin Reverses Placenta-Induced Fibrosis of Umbilical Arteries in Preeclampsia.International journal of molecular sciences · 2018Article
- Placental Nkx2-5 and target gene expression in early-onset and severe preeclampsia.Hypertension in pregnancy · 2014Article
- Magnesium sulfate potentiates effect of DigiFab on marinobufagenin-induced Na/K-ATPase inhibition.American journal of hypertension · 2013Article
- Genetic and environmental factors influencing the Placental Growth Factor (PGF) variation in two populations.PloS one · 2012Article
- The adaptation of the blood-brain barrier to vascular endothelial growth factor and placental growth factor during pregnancy.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2012Article
- Placental lesions associated with maternal underperfusion are more frequent in early-onset than in late-onset preeclampsia.Journal of perinatal medicine · 2011Article
- Pathogenesis and treatment of bronchopulmonary dysplasia.Current opinion in pediatrics · 2011Review
- Antepartum eclampsia <34 weeks case series: advisable to postpone delivery to administer corticosteroids for fetal pulmonary benefit?Journal of perinatology : official journal of the California Perinatal Association · 2011Article
- Effects of maternal serum on permeability of glomerular endothelial cell membrane.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2011Article
- Maternal gene expression profiling during pregnancy and preeclampsia in human peripheral blood mononuclear cells.Placenta · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preeclampsia, a serious hypertensive complication of pregnancy characterized by new-onset hypertension and proteinuria after midpregnancy, is a multisystem disorder that often involves the central nervous system. Neurologic signs and symptoms include hyperreflexia, headaches, visual disturbance, seizures, and cerebral hemorrhage. Eclampsia-new-onset seizures in the setting of preeclampsia-usually occurs before or within 48 hours of delivery, but can present as late as 1 month postpartum (late postpartum eclampsia). Magnesium sulfate is the drug of choice to prevent and treat eclampsia, a recommendation validated through large, randomized, and placebo-controlled trials. This review describes the pathogenesis, clinical features, and treatment of eclampsia, focusing on recent observations regarding roles of circulating antiangiogenic factors in the pathogenesis of the neurologic complications of eclampsia.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.