ArticlePlant molecular biology2008
Heterologous expression of a plastid EF-Tu reduces protein thermal aggregation and enhances CO2 fixation in wheat (Triticum aestivum) following heat stress.
Article in Plant molecular biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 79 citations in OpenAlex.
- Design Principles of Plant Thermotolerance: Integrating Photosynthesis, Reproduction, and Field Resilience in a Warming Climate.Plant, cell & environment · 2026Review
- Comparative physiological and transcriptomic analyses identify computationally predicted key genes and regulatory pathways in non-heading Chinese cabbage under heat stress.BMC plant biology · 2025Article
- Enhancing wheat resilience: biotechnological advances in combating heat stress and environmental challenges.Plant molecular biology · 2025Review
- Development of Modified Farquhar-von Caemmerer-Berry Model Describing Photodamage of Photosynthetic Electron Transport in CPlants (Basel, Switzerland) · 2023Article
- TheAutophagy · 2023Article
- Chloroplast translation factor EF-Tu of Arabidopsis thaliana can be inactivated via oxidation of a specific cysteine residue.The Biochemical journal · 2023Article
- Genetic variation for terminal heat stress tolerance in winter wheat.Frontiers in plant science · 2023Article
- Candidate Genes Associated with Abiotic Stress Response in Plants as Tools to Engineer Tolerance to Drought, Salinity and Extreme Temperatures in Wheat: An Overview.Plants (Basel, Switzerland) · 2022Review
- Physiological and molecular insights on wheat responses to heat stress.Plant cell reports · 2022Review
- Biological Parts for Engineering Abiotic Stress Tolerance in Plants.Biodesign research · 2022Review
- Wheat heat tolerance is impaired by heightened deletions in the distal end of 4AL chromosomal arm.Plant biotechnology journal · 2021Article
- DNA Demethylation in Response to Heat Stress inInternational journal of molecular sciences · 2021Article
- Rising Atmospheric Temperature Impact on Wheat and Thermotolerance Strategies.Plants (Basel, Switzerland) · 2020Review
- Feeling the heat: developmental and molecular responses of wheat and barley to high ambient temperatures.Journal of experimental botany · 2020Review
- Molecular and genetic bases of heat stress responses in crop plants and breeding for increased resilience and productivity.Journal of experimental botany · 2020Review
- Light-inducible expression of translation factor EF-Tu during acclimation to strong light enhances the repair of photosystem II.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Can wheat survive in heat? Assembling tools towards successful development of heat stress tolerance in Triticum aestivum L.Molecular biology reports · 2019Review
- Plastid Translation Elongation Factor Tu Is Prone to Heat-Induced Aggregation Despite Its Critical Role in Plant Heat Tolerance.Plant physiology · 2018Article
- Heat and Drought Stresses in Crops and Approaches for Their Mitigation.Frontiers in chemistry · 2018Review
- Expression of a rice soluble starch synthase gene in transgenic wheat improves the grain yield under heat stress conditions.In vitro cellular & developmental biology. Plant : journal of the Tissue Culture Association · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat stress is a major constraint to wheat production and negatively impacts grain quality, causing tremendous economic losses, and may become a more troublesome factor due to global warming. At the cellular level, heat stress causes denaturation and aggregation of proteins and injury to membranes leading to alterations in metabolic fluxes. Protein aggregation is irreversible, and protection of proteins from thermal aggregation is a strategy a cell uses to tolerate heat stress. Here we report on the development of transgenic wheat (Triticum aestivum) events, expressing a maize gene coding for plastidal protein synthesis elongation factor (EF-Tu), which, compared to non-transgenic plants, display reduced thermal aggregation of leaf proteins, reduced heat injury to photosynthetic membranes (thylakoids), and enhanced rate of CO(2) fixation after exposure to heat stress. The results support the concept that EF-Tu ameliorates negative effects of heat stress by acting as a molecular chaperone. This is the first demonstration of the introduction of a plastidal EF-Tu in plants that leads to protection against heat injury and enhanced photosynthesis after heat stress. This is also the first demonstration that a gene other than HSP gene can be used for improvement of heat tolerance and that the improvement is possible in a species that has a complex genome, hexaploid wheat. The results strongly suggest that heat tolerance of wheat, and possibly other crop plants, can be improved by modulating expression of plastidal EF-Tu and/or by selection of genotypes with increased endogenous levels of this protein.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.