SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2008
Mechanical bowel preparation in intestinal surgery: a meta-analysis and review of the literature.
Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- Effectiveness of mechanical bowel preparation versus no preparation on anastomotic leakage in colorectal surgery: a systematic review and meta-analysis.Updates in surgery · 2019Pooled it
- Mechanical bowel preparation for elective colorectal surgery: updated systematic review and meta-analysis.International journal of colorectal disease · 2012Pooled it
- Risk of anastomotic leakage with use of NSAIDs after gastrointestinal surgery.International journal of colorectal disease · 2011Pooled it
- Preoperative bowel preparation for patients undergoing elective colorectal surgery: a clinical practice guideline endorsed by the Canadian Society of Colon and Rectal Surgeons.Canadian journal of surgery. Journal canadien de chirurgie · 2010Guideline
- Trial
- Mechanical bowel preparation for children undergoing elective colorectal surgery.Journal of pediatric gastroenterology and nutrition · 2015Trial
- Significant changes in the intestinal environment after surgery in patients with colorectal cancer.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013Trial
- Evaluating Mechanical Bowel Preparation Prior to Total Laparoscopic Hysterectomy.JSLS : Journal of the Society of Laparoendoscopic SurgeonsTrial
- Pre-Operative Mechanical Bowel Preparation Does Not Affect the Impact of Anastomosis Leakage in Left-Side Colorectal Surgery-A Single Center Observational Study.Life (Basel, Switzerland) · 2024Article
- Fast-track surgery with three-port versus conventional perioperative management of bladder cancer associated laparoscopic radical cystectomy and Ileal conduit diversion: Chinese experience.World journal of surgical oncology · 2024Article
- The Impact of Surgical Bowel Preparation on the Microbiome in Colon and Rectal Surgery.Antibiotics (Basel, Switzerland) · 2024Review
- Perioperative Considerations for the Surgical Treatment of Crohn's Disease with Discussion on Surgical Antibiotics Practices and Impact on the Gut Microbiome.Antibiotics (Basel, Switzerland) · 2024Review
- The Influence of the Microbiome on Anastomotic Leak.Clinics in colon and rectal surgery · 2023Review
- A Review of Bowel Preparation Before Colorectal Surgery.Annals of coloproctology · 2021Review
- Article
- Role of oral antibiotics for prophylaxis against surgical site infections after elective colorectal surgery.World journal of gastrointestinal surgery · 2017Review
- Surgical Technical Evidence Review for Colorectal Surgery Conducted for the AHRQ Safety Program for Improving Surgical Care and Recovery.Journal of the American College of Surgeons · 2017Review
- American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statement on prevention of postoperative infection within an enhanced recovery pathway for elective colorectal surgery.Perioperative medicine (London, England) · 2017Article
- Fast-track laparoscopic surgery: A better option for treating colorectal cancer than conventional laparoscopic surgery.Oncology letters · 2015Article
- Colectomy without mechanical bowel preparation in the private practice setting.Techniques in coloproctology · 2014Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDespite several meta-analyses and randomized controlled trials showing no benefit to patients, mechanical bowel preparation (MBP) remains the standard of practice for patients undergoing elective colorectal surgery.
methodsWe performed a systematic review of the literature of trials that prospectively compared MBP with no MBP for patients undergoing elective colorectal resection. We searched MEDLINE, LILACS, and SCISEARCH, abstracts of pertinent scientific meetings and reference lists for each article found. Experts in the field were queried as to knowledge of additional reports. Outcomes abstracted were anastomotic leaks and wound infections. Meta-analysis was performed using Peto Odds ratio.
resultsOf 4,601 patients (13 trials), 2,304 received MBP (Group 1) and 2,297 did not (Group 2). Anastomotic leaks occurred in 97(4.2%) patients in Group 1 and in 81(3.5%) patients in Group 2 (Peto OR = 1.214, CI 95%:0.899-1.64, P = 0.206). Wound infections occurred in 227(9.9%) patients in Group 1 and in 201(8.8%) patients in Group 2 (Peto OR = 1.156, CI 95%:0.946-1.413, P = 0.155). DISCUSSION: This meta-analysis demonstrates that MBP provides no benefit to patients undergoing elective colorectal surgery, thus, supporting elimination of routine MBP in elective colorectal surgery.
conclusionIn conclusion, MBP is of no benefit to patients undergoing elective colorectal resection and need not be recommended to meet "standard of care."
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.