ArticleIntensive care medicine2008
Risk factors and prognosis of catheter-related bloodstream infection in critically ill patients: a multicenter study.
Article in Intensive care medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 151 citations in OpenAlex.
- Risk factors of catheter- associated bloodstream infection: Systematic review and meta-analysis.PloS one · 2023Pooled it
- The effect of diabetes on mortality in critically ill patients: a systematic review and meta-analysis.Critical care (London, England) · 2011Pooled it
- Guidewire exchange vs new site placement for temporary dialysis catheter insertion in ICU patients: is there a greater risk of colonization or dysfunction?Critical care (London, England) · 2016Trial
- Risk Factor Prediction Model for Catheter-Associated Bloodstream Infections (CABSIs) in Midline and Central Venous Catheters: A Cohort Follow-Up Study.Journal of clinical medicine · 2026Article
- Practice guideline on the prevention and treatment of central line-associated bloodstream infection: Part 1--Diagnosis and prevention.Journal of intensive medicine · 2026Article
- Source control in bloodstream infections in patients with sepsis, septic shock, or requiring ICU admission: a scoping review with recommendations for standardizing research.Intensive care medicine · 2025Article
- Jugular Venous Catheterization is Not Associated with Increased Complications in Patients with Aneurysmal Subarachnoid Hemorrhage.Neurocritical care · 2025Article
- Association of Extended Steroid Treatment With Bloodstream Infection in Critically Ill Patients With COVID-19: A National, Multicenter, Propensity Score-Matched Study.Journal of Korean medical science · 2025Article
- The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2024.Journal of intensive care · 2025Article
- Article
- Reassessing the need for scheduled replacement of short term central venous catheters: A narrative comprehensive review.Infection prevention in practice · 2024Review
- Business Process Model and Notation and openEHR Task Planning for Clinical Pathway Standards in Infections: Critical Analysis.Journal of medical Internet research · 2022Article
- Hemodialysis Catheters: Update on Types, Outcomes, Designs and Complications.Seminars in interventional radiology · 2022Review
- Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.Intensive care medicine · 2021Article
- Occurrence and incidence rate of peripheral intravascular catheter-related phlebitis and complications in critically ill patients: a prospective cohort study (AMOR-VENUS study).Journal of intensive care · 2021Article
- Clinical Observation and Prognostic Analysis of Patients WithFrontiers in cellular and infection microbiology · 2020Article
- Practical approach to the management of catheter-related bloodstream infection.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2019Review
- Home Parenteral Nutrition in Patients with Intestinal Failure: Possible Undetected Complications.Nutrients · 2019Article
- The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016).Journal of intensive care · 2018Article
- The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016).Acute medicine & surgery · 2018Article
Corrections and comments
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Authors and funding
13 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the risk factors associated with CR-BSI development in critically ill patients with non-tunneled, non-cuffed central venous catheters (CVC) and the prognosis of the episodes of CR-BSI. Design and setting; prospective, observational, multicenter study in nine Spanish Hospitals. PATIENTS: All subjects admitted to the participating ICUs from October 2004 to June 2005 with a CVC.
interventionsNone. MEASUREMENT AND
resultsOverall, 1,366 patients were enrolled and 2,101 catheters were analyzed. Sixty-six episodes of CR-BSI were diagnosed. The incidence of CR-BSI was significantly higher in CVC compared with peripherically inserted central venous catheters (PICVC) without significant differences among the three locations of CVC. In the multivariate analysis, duration of catheterization and change over a guidewire were the independent variables associated with the development of CR-BSI whereas the use of a PICVC was a protective factor. Excluding PICVC, 1,598 conventional CVC were analyzed. In this subset, duration of catheterization, tracheostomy and change over a guidewire were independent risk factors for CR-BSI. A multivariate analysis of predictors for mortality among 66 patients with CRSI showed that early removal of the catheter was a protective factor and APACHE II score at the admission was a strong determinant of in-hospital mortality.
conclusionsPeripherically inserted central venous catheters is associated with a lower incidence of CR-BSI in critically ill patients. Exchange over a guidewire of CVC and duration of catheterization are strong contributors to CR-BSI. Our results reinforce the importance of early catheter removal in critically ill patients with CR-BSI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.