ArticleGenetics2008
Linkage disequilibrium and persistence of phase in Holstein-Friesian, Jersey and Angus cattle.
Article in Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 217 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
217 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Genome-wide association analysis using multiple Atlantic salmon populations.Genetics, selection, evolution : GSE · 2025Pooled it
- MetaGS: an accurate method to impute and combine SNP effects across populations using summary statistics.Genetics, selection, evolution : GSE · 2022Pooled it
- Meta-analysis for milk fat and protein percentage using imputed sequence variant genotypes in 94,321 cattle from eight cattle breeds.Genetics, selection, evolution : GSE · 2020Pooled it
- From family trials to genomic mate allocation: statistical and genomic strategies to accelerate sugarcane genetic improvement.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Review
- Resolving Cattle GWAS Loci: Current Progress, Persistent Challenges and Future Directions.Current issues in molecular biology · 2026Review
- Investigating the genetic basis of susceptibility to amoebic gill disease and idiopathic gill lesions in Atlantic salmon populations using field data.Genetics, selection, evolution : GSE · 2026Article
- Genetic diversity and population structure of U.S. Suffolk sheep participating in the national sheep improvement program.Genetics, selection, evolution : GSE · 2026Article
- An Increase in Male Recombination Rate With Age in Dairy Cattle Is Heritable and Polygenic.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2026Article
- Genomic scans for diversity and selection signatures in Indian Red Sindhi cattle.Mammalian genome : official journal of the International Mammalian Genome Society · 2025Article
- Remarkable heterogeneity revealed in the genetic architecture of resistance to a key bacterial pathogen in two commercial rainbow trout populations.BMC genomics · 2025Article
- Estimating Linkage Disequilibrium and Effective Population Size Across Generations in Holstein Cattle.Veterinary medicine and science · 2025Article
- Mapping genes for resilient dairy cows by means of across-breed genome-wide association analysis.BMC genomics · 2025Article
- Shared SNP effects across breeds increase the genomic prediction accuracy for numerically small breeds.Scientific reports · 2025Article
- Genomic selection with GWAS-identified QTL markers enhances prediction accuracy for quantitative traits in poplar (Populus deltoides).Communications biology · 2025Article
- Population structure limits the use of genomic data for predicting phenotypes and managing genetic resources in forest trees.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Enhancing Genomic Prediction Accuracy with a Single-Step Genomic Best Linear Unbiased Prediction Model Integrating Genome-Wide Association Study Results.Animals : an open access journal from MDPI · 2025Article
- Optimizing multi-breed joint genomic prediction issues in numerically small breeds for sex-limited trait in a loosely structured dairy cattle breeding system.Tropical animal health and production · 2025Article
- An overview of recent technological developments in bovine genomics.Veterinary and animal science · 2024Review
- Article
- Accuracy of genomic prediction using multiple Atlantic salmon populations.Genetics, selection, evolution : GSE · 2024Article
157 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When a genetic marker and a quantitative trait locus (QTL) are in linkage disequilibrium (LD) in one population, they may not be in LD in another population or their LD phase may be reversed. The objectives of this study were to compare the extent of LD and the persistence of LD phase across multiple cattle populations. LD measures r and r(2) were calculated for syntenic marker pairs using genomewide single-nucleotide polymorphisms (SNP) that were genotyped in Dutch and Australian Holstein-Friesian (HF) bulls, Australian Angus cattle, and New Zealand Friesian and Jersey cows. Average r(2) was approximately 0.35, 0.25, 0.22, 0.14, and 0.06 at marker distances 10, 20, 40, 100, and 1000 kb, respectively, which indicates that genomic selection within cattle breeds with r(2) >or= 0.20 between adjacent markers would require approximately 50,000 SNPs. The correlation of r values between populations for the same marker pairs was close to 1 for pairs of very close markers (<10 kb) and decreased with increasing marker distance and the extent of divergence between the populations. To find markers that are in LD with QTL across diverged breeds, such as HF, Jersey, and Angus, would require approximately 300,000 markers.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.