ArticleJournal of feline medicine and surgery2008
Evaluation of pradofloxacin for the treatment of feline rhinitis.
Article in Journal of feline medicine and surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases.Journal of veterinary internal medicine · 2017Guideline
- A Review of Fluoroquinolones with a Focus on Veterinary-Approved Agents.Biomolecules · 2026Review
- Presumed Primary Bacterial Rhinosinusitis-Associated Optic Neuritis in a Cat.Frontiers in veterinary science · 2020Article
- Feline upper respiratory tract infection and disease in Australia.Journal of feline medicine and surgery · 2019Article
- Article
- Update in feline therapeutics: clinical use of 10 emerging therapies.Journal of feline medicine and surgery · 2015Review
- Feline respiratory disease: what is the role of Mycoplasma species?Journal of feline medicine and surgery · 2014Review
- 2013 AAFP Feline Vaccination Advisory Panel Report.Journal of feline medicine and surgery · 2013Article
- Nasopharyngeal disease in cats: 2. Specific conditions and their management.Journal of feline medicine and surgery · 2012Review
- Snots and snuffles: rational approach to chronic feline upper respiratory syndromes.Journal of feline medicine and surgery · 2010Review
- Effect of sample collection methodology on nasal culture results in cats.Journal of feline medicine and surgery · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Forty humane society cats with suspected bacterial upper respiratory infections (URIs) were studied in order to compare amoxycillin and pradofloxacin for treatment of rhinitis and describe common pathogens. Nasal discharges were collected prior to random placement into one of three treatment groups. Cats failing to initially respond were crossed to the alternate drug. Drug toxicity was not noted. The organisms most frequently isolated or amplified pre-treatment were feline herpesvirus-1 (75%), Mycoplasma species (62.5%), Bordetella species (47.5%), Staphylococcus species (12.5%) and Streptococcus species (10.0%). No differences in clinical scores between groups over time were noted. Overall response rates for amoxycillin at 22 mg/kg, q12 h for seven doses (10/15 cats; 67%), pradofloxacin at 5mg/kg, q24 h for seven doses (11/13 cats; 85%), and pradofloxacin at 10mg/kg, q24 h for seven doses (11/12 cats; 92%) were not statistically significant. Results suggest that pradofloxacin can be a safe, efficacious therapy for some cats with suspected bacterial URI.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.