ArticleGenes, brain, and behavior2008
Systematic analysis of emotionality in consomic mouse strains established from C57BL/6J and wild-derived MSM/Ms.
Article in Genes, brain, and behavior, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 45 citations in OpenAlex.
- Contributions of sex and genotype to exploratory behavior differences in an aged humanizedLearning & memory (Cold Spring Harbor, N.Y.) · 2022Article
- Intrauterine inflammation induces sex-specific effects on neuroinflammation, white matter, and behavior.Brain, behavior, and immunity · 2017Article
- Genetic Dissection of Trabecular Bone Structure with Mouse Intersubspecific Consomic Strains.G3 (Bethesda, Md.) · 2017Article
- Hierarchy in the home cage affects behaviour and gene expression in group-housed C57BL/6 male mice.Scientific reports · 2017Article
- Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.PloS one · 2016Article
- Article
- Segregation of a QTL cluster for home-cage activity using a new mapping method based on regression analysis of congenic mouse strains.Heredity · 2014Article
- The ancestor of extant Japanese fancy mice contributed to the mosaic genomes of classical inbred strains.Genome research · 2013Article
- Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2013Article
- Deconstructing Mus gemischus: advances in understanding ancestry, structure, and variation in the genome of the laboratory mouse.Mammalian genome : official journal of the International Mammalian Genome Society · 2013Review
- Individual differences and the characterization of animal models of psychopathology: a strong challenge and a good opportunity.Frontiers in pharmacology · 2013Review
- Chromosome substitution strains: gene discovery, functional analysis, and systems studies.Mammalian genome : official journal of the International Mammalian Genome Society · 2012Review
- Exercise offers anxiolytic potential: a role for stress and brain noradrenergic-galaninergic mechanisms.Neuroscience and biobehavioral reviews · 2012Review
- Forward genetic approaches to understanding complex behaviors.Current topics in behavioral neurosciences · 2012Review
- Sex-dependent novelty response in neurexin-1α mutant mice.PloS one · 2012Article
- The autism diagnosis in translation: shared affect in children and mouse models of ASD.Autism research : official journal of the International Society for Autism Research · 2011Review
- The influence of sex and estrous cycle on QTL for emotionality and ethanol consumption.Mammalian genome : official journal of the International Mammalian Genome Society · 2011Article
- Variations in Maternal Behavior in C57BL/6J Mice: Behavioral Comparisons between Adult Offspring of High and Low Pup-Licking Mothers.Frontiers in psychiatry · 2011Article
- QTL analysis of measures of mouse home-cage activity using B6/MSM consomic strains.Mammalian genome : official journal of the International Mammalian Genome Society · 2010Article
- Transgenerational genetic effects of the paternal Y chromosome on daughters' phenotypes.Epigenomics · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Consomic strains have recently attracted attention as an advantageous method to screen for genes related to developmental, physiological, and behavioral phenotypes. Recently, a new set of consomic strains was established from the Japanese wild-derived mouse strain MSM/Ms and C57BL/6JJcl. By analyzing the entire consomic panel, we were able to identify a number of chromosomes associated with anxiety-like behaviors in the open-field (OF) test, a light-dark box and an elevated plus maze. Detailed observation of the OF behavior allowed us to identify chromosomes associated with those ethological traits, such as stretch attend, rearing, and jumping. Repeated OF test trials have different meanings for animals, and we found that some chromosomes responded to only the first or second trial, while others were consistent across both trials. By examining both male and female mice, sex-dependent effects were found in several measurements. Principal component analysis of anxiety-like behaviors extracted five factors: 'general locomotor activity', 'thigmotaxis', 'risk assessment', 'open-arm exploration' and 'autonomic emotionality'. We mapped chromosomes associated with these five factors of emotionality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.