Ace inhibitors as a therapy for sarcopenia - evidence and possible mechanisms.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Effect of Angiotensin System Inhibitors on Physical Performance in Older People - A Systematic Review and Meta-Analysis.Journal of the American Medical Directors Association · 2021
   Pooled it
2. ACE I/D genotype associates with strength in sarcopenic men but not with response to ACE inhibitor therapy in older adults with sarcopenia: Results from the LACE trial.PloS one · 2023
   Trial
3. Effect of Antihypertensive and Statin Medication Use on Muscle Performance in Community-Dwelling Older Adults Performing Strength Training.Drugs & aging · 2021
   Trial
4. Research progress on the diagnosis and pathogenesis of chronic heart failure combined with sarcopenia.Journal of cardiothoracic surgery · 2026
   Review
5. Pain Increases the Risk for Sarcopenia in Community-Dwelling Adults: Results From the English Longitudinal Study of Ageing.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
   Article
6. Locomotor and respiratory muscle abnormalities in HFrEF and HFpEF.Frontiers in cardiovascular medicine · 2023
   Review
7. The Role of Sarcopenia in Heart Failure with Depression.Reviews in cardiovascular medicine · 2022
   Review
8. Muscle Wasting and Sarcopenia in Heart Failure-The Current State of Science.International journal of molecular sciences · 2020
   Review
9. Milk for Skeletal Muscle Health and Sarcopenia in Older Adults: A Narrative Review.Clinical interventions in aging · 2020
   Review
10. Leucine and ACE inhibitors as therapies for sarcopenia (LACE trial): study protocol for a randomised controlled trial.Trials · 2018
    Article
11. Molecular mechanisms and therapeutic interventions in sarcopenia.Osteoporosis and sarcopenia · 2017
    Review
12. Pre-sarcopenia is associated with renal hyperfiltration independent of obesity or insulin resistance: Nationwide Surveys (KNHANES 2008-2011).Medicine · 2017
    Observational
13. Angiotensin-Converting Enzyme Inhibitors and Parameters of Sarcopenia: Relation to Muscle Mass, Strength and Function: Data from the Berlin Aging Study-II (BASE-II).Drugs & aging · 2016
    Article
14. Impact of nutrition on muscle mass, strength, and performance in older adults.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013
    Review
15. Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update.Clinical interventions in aging · 2010
    Review
16. Functional consequences of sarcopenia and dynapenia in the elderly.Current opinion in clinical nutrition and metabolic care · 2010
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

4 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as