Evidence map›Paper›PMID 18615225›Full record

ReviewThe journal of nutrition, health & aging

Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives.

Y Rolland, S Czerwinski, G Abellan Van Kan, J E Morley, M Cesari, G Onder, J Woo, R Baumgartner, F Pillard, Y Boirie and 2 more

3 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The journal of nutrition, health & aging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 431 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
431citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02297997 early_phase1completednot on this map

Randomized, Double Blinded, Placebo-controlled Trial to Assess the Preventive Effects of Cetylpyridinium Chloride on Sarcopenia: An Exploratory Pilot Study

TypeinterventionalSponsorSeoul National University HospitalRan2014 to 2015Enrolled65ConditionsSarcopeniaArmscetylpyridinium chloride, Placebo
NCT02575235 early_phase1completednot on this map

Randomized, Double Blinded, Placebo-controlled Trial to Assess the Preventive Effects of Cetylpyridinium Chloride on Sarcopenia

TypeinterventionalSponsorSeoul National University HospitalRan2015 to 2016Enrolled100ConditionsSarcopeniaArmsCetylpyridinium Chloride (CPC), placebo
NCT07253714 nacompletednot on this map

The effect of proprioceptive exercise training on cervical proprioception, kinesiophobia, and pain catastrophizing levels in sarcopenic geriatric individuals residing in nursing homes

TypeinterventionalSponsorAtılım UniversityRan2024 to 2024Enrolled31ConditionsSarcopenia in ElderlyArmsClassic exercises, Proprioceptive exercise training
3 · Its place in the literature

Who cites it

431 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Trial
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  13. Visceral Fat Obesity Correlates with Frailty in Middle-Aged and Older Adults.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Trial
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371 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Y RollandInserm U558, F-31073Toulouse, France. rolland.y@chu-toulouse.fr
S Czerwinski
G Abellan Van Kan
J E Morley
M Cesari
G Onder
J Woo
R Baumgartner
F Pillard
Y Boirie
W M C Chumlea
B Vellas

Funding

SUBCUTANEOUS FAT, BLOOD LIPIDS AND SUBSEQUENT OUTCOMER01HD012252 · NICHD · WRIGHT STATE UNIVERSITY · PI CZERWINSKI, STEFAN A. · 1985 to 2014
$17.3M
Genetic Analysis of Osteoporosis Risk FactorsR01AR052147 · NIAMS · WRIGHT STATE UNIVERSITY · PI CZERWINSKI, STEFAN A. · 2005 to 2009
$2.2M
NIAMS NIH HHS R01 AR052147NICHD NIH HHS R01 HD012252
6 · The paper itself

Abstract

Sarcopenia is a loss of muscle protein mass and loss of muscle function. It occurs with increasing age, being a major component in the development of frailty. Current knowledge on its assessment, etiology, pathogenesis, consequences and future perspectives are reported in the present review. On-going and future clinical trials on sarcopenia may radically change our preventive and therapeutic approaches of mobility disability in older people.

Indexed as

Muscular AtrophyAgedAged, 80 and overAgingExerciseFrail ElderlyHumansMuscle, Skeletal

Identifiers

PMID18615225
PMCPMC3988678

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.