Evidence map›Paper›PMID 18612761›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2008

The protective effect of fish n-3 fatty acids on cerebral ischemia in rat prefrontal cortex.

Oguz Aslan Ozen, Murat Cosar, Onder Sahin, Huseyin Fidan, Olcay Eser, Hakan Mollaoglu, Ozan Alkoc, Mehmet Yaman, Ahmet Songur

Abstract read
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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Role of Omega-3 Polyunsaturated Fatty Acids in Stroke.Oxidative medicine and cellular longevity · 2016
    Review
  10. Article
  11. Article
  12. Article
  13. Vascular aspects of cognitive impairment and dementia.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2013
    Review
  14. Article
  15. Expression of Bcl-2 and Bax after hippocampal ischemia in DHA + EPA treated rats.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Oguz Aslan OzenKocatepe University, School of Medicine, Department of Anatomy, Afyonkarahisar, Turkey.
Murat Cosar
Onder Sahin
Huseyin Fidan
Olcay Eser
Hakan Mollaoglu
Ozan Alkoc
Mehmet Yaman
Ahmet Songur
Afyon Kocatepe University · TRFundación Juan March · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents neuroprotective effects of fish n-3 EFA on the prefrontal cortex after cerebral ischemia and reperfusion. Eighteen rats divided into three groups. Group A rats were used as control. Cerebral ischemia and reperfusion was produced in rats either on a standard diet (Group B) or a standard diet plus fish n-3 EFA for 14 days (Group C). The malondialdehyde (MDA) levels and activities of superoxide dismutase (SOD) and catalase (CAT) were measured and the number of apoptotic neurons was counted. The levels of MDA and activities of SOD increased in Group B rats as compared to Group A rats, and decreased in Group C rats as compared to Group B rats. The activities of CAT increased in Group C as compared to Group B rats. The number of apoptotic neurons in the prefrontal cortex was lower in Group C as compared to Group B rats.

Indexed as

AnimalsApoptosisBiomarkersBrain IschemiaCatalaseCell CountCerebral InfarctionDietary FatsDisease Models, AnimalFatty Acids, Omega-3Fish ProductsFood, FormulatedMaleMalondialdehydeNerve DegenerationNeuroprotective AgentsBiomarkersCatalaseDietary FatsFatty Acids, Omega-3MalondialdehydeNeuroprotective AgentsSuperoxide Dismutase

Identifiers

PMID18612761
OpenAlexW2053705731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.