ArticleSchmerz (Berlin, Germany)2008
[Indications and use of benzodiazepines in a palliative care unit].
Article in Schmerz (Berlin, Germany), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- [Drug therapy of anxiety and fear in palliative care patients with cancer or other illnesses : a systematic review].Schmerz (Berlin, Germany) · 2012Pooled it
- Impact of palliative care at end-of-life Covid-19 patients - a small-scale pioneering experience.BMC palliative care · 2024Article
- Bladder Care in Palliative Care Inpatients: A Prospective Dual Site Cohort Study.Palliative medicine reports · 2020Article
- Palliative sedation in Germany: factors and treatment practices associated with different sedation rate estimates in palliative and hospice care services.BMC palliative care · 2018Article
- The EAPC framework on palliative sedation and clinical practice--a questionnaire-based survey in Germany.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2014Article
- [Pain, suffering and compassion : guidance in dealing with death].Schmerz (Berlin, Germany) · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBenzodiazepines are often used in palliative care for symptom control, for example in treatment of dyspnea or anxiety. They are also used for palliative sedation, if symptoms are not controlled (fast) enough and a reduction of consciousness is therefore necessary. Incidence of palliative sedation has been reported to vary between 5-52% of all patients in a palliative care setting in several studies.
methodInformation from the records of 160 patients treated in the palliative care unit from September 2003 to December 2004 was evaluated from an electronic database. Gender, age, diagnosis, symptoms and medication, especially benzodiazepine dosage and application were analyzed.
resultOf the patients 70% were treated with benzodiazepines but only 3.1% received deep and continuous sedation. Benzodiazepines were applied as required in oral or sublingual form in 71.8% of all cases. Lorazepam was given most often because of anxiety and agitation, oxazepam to induce sleep and midazolam in five cases of terminal sedation. Only rarely were diazepam and clonazepam prescribed to prevent or resolve convulsions.
conclusionThe majority of patients had been treated with benzodiazepines whereas only very few had received deep and continuous sedation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.