Evidence map›Paper›PMID 18608084›Full record

ArticleAIDS care2008

Measuring fatigue in people living with HIV/AIDS: psychometric characteristics of the HIV-related fatigue scale.

B W Pence, J Barroso, J Leserman, J L Harmon, N Salahuddin

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  7. Article
  8. Fatigue in HIV-Infected People: A Three-Year Observational Study.Journal of pain and symptom management · 2015
    Observational
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  16. A 7-item version of the fatigue severity scale has better psychometric properties among HIV-infected adults: an application of a Rasch model.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2011
    Article
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

B W PenceSanford Institute of Public Policy, Duke University, Durham, NC, USA. bpence@aya.yale.edu
J Barroso
J Leserman
J L Harmon
N Salahuddin
Duke University · USDuke Institute for Health Innovation · USUniversity of North Carolina at Chapel Hill · US

Funding

Pilot Project for the DTMI CRA ProgramUL1RR024128 · NCRR · DUKE UNIVERSITY · PI CALIFF, ROBERT M · 2006 to 2010
$48.1M
Fatigue in HIV-Positive PeopleR01NR008681 · NINR · DUKE UNIVERSITY · PI BARROSO, JULIE V · 2004 to 2008
$2.5M
NCRR NIH HHS 1UL1RR024128-01NCRR NIH HHS UL1 RR024128NINR NIH HHS 5R01NR008681NINR NIH HHS R01 NR008681
6 · The paper itself

Abstract

In the era of life-prolonging antiretroviral therapy, chronic fatigue is one of the most prevalent and disabling symptoms of people living with HIV/AIDS, yet its measurement remains challenging. No instruments have been developed specifically to describe HIV-related fatigue. We assessed the reliability and construct validity of the HIV-Related Fatigue Scale (HRFS), a 56-item self-report instrument developed through formative qualitative research and designed to measure the intensity and consequences of fatigue as well as the circumstances surrounding fatigue in people living with HIV. The HRFS has three main scales, which measure fatigue intensity, the responsiveness of fatigue to circumstances and fatigue-related impairment of functioning. The functioning scale can be further divided into subscales measuring impairment of activities of daily living, impairment of mental functioning and impairment of social functioning. Each scale demonstrated high internal consistency (Cronbach's alpha=0.93, 0.91 and 0.97 for the intensity, responsiveness and functioning scales, respectively). The HRFS scales also demonstrated satisfactory convergent validity when compared to other fatigue measures. HIV-Related Fatigue Scales were moderately correlated with quality of nighttime sleep (rho=0.46, 0.47 and 0.35) but showed only weak correlations with daytime sleepiness (rho=0.20, 0.33 and 0.18). The scales were also moderately correlated with general mental and physical health as measured by the SF-36 Health Survey (rho ranged from 0.30 to 0.68 across the 8 SF-36 subscales with most >0.40). The HRFS is a promising tool to help facilitate research on the prevalence, etiology and consequences of fatigue in people living with HIV.

Indexed as

Activities of Daily LivingHIV-1AdultFatigueFemaleHealth SurveysHIV InfectionsHumansLongitudinal StudiesMalePsychometricsResearch DesignSensitivity and SpecificitySeverity of Illness IndexSoutheastern United StatesSurveys and Questionnaires

Identifiers

PMID18608084
PMCPMC2586613
OpenAlexW2060804242

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.