ArticleJournal of fluorescence2009
Studies on interaction of CdTe quantum dots with bovine serum albumin using fluorescence correlation spectroscopy.
Article in Journal of fluorescence, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Mechanistic interaction studies of synthesized ZIF-8 nanoparticles with bovine serum albumin using spectroscopic and molecular docking approaches.Scientific reports · 2022Article
- Blood group antigen studies using CdTe quantum dots and flow cytometry.International journal of nanomedicine · 2015Article
- CdTe quantum dots enhance feasibility of EvaGreen-based real-time PCR with decent amplification fidelity.Molecular biotechnology · 2013Article
- Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin.Nanoscale research letters · 2011Article
- Fluctuation methods to study protein aggregation in live cells: concanavalin A oligomers formation.Biophysical journal · 2011Article
- Differential modulation of the active site environment of human carbonic anhydrase XII by cationic quantum dots and polylysine.Biochimica et biophysica acta · 2010Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Luminescent quantum dots (QDs) have widely used in some biological and biomedical fields due to their unique and fascinating optical properties, meanwhile the interaction of QDs with biomolecules recently attract increasing attention. In this paper, we employed fluorescence correlation spectroscopy (FCS) to investigate the nonspecific interaction between CdTe QDs and bovine serum albumin (BSA) as a model, and evaluate their stoichiometric ratio and association constant. Our results documented that BSA was able to bind to CdTe QDs and form the QD-BSA complex by a 1:1 stoichiometric ratio. The association constant evaluated is 1.06+/-0.14x10(7) M(-1) in 0.01 M phosphate buffer (pH=7.4). Furthermore, we found that QD-BSA complex dissociated with increase of ion strength, and we speculated that the interaction of CdTe QDs with BSA was mainly attributed to electrostatic attraction. Our preliminary results demonstrate that fluorescence correlation spectroscopy is an effective tool for investigation of the interaction between quantum dots (or nanoparticles) and biomolecules.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.