ReviewDiabetologia2008
Non-invasive cardiac imaging techniques and vascular tools for the assessment of cardiovascular disease in type 2 diabetes mellitus.
Review in Diabetologia, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Diagnosis, prevention, and treatment of cardiovascular diseases in people with type 2 diabetes and prediabetes: a consensus statement jointly from the Japanese Circulation Society and the Japan Diabetes Society.Diabetology international · 2021Guideline
- Decreased PECAM-1 May be a potential pathological factor for vascular injury in T2DM patients.Scientific reports · 2025Article
- Left Ventricular Wall Motion as an Additional Valuable Parameter in Diabetic Patients with Normal Myocardial Perfusion Imaging.Current radiopharmaceuticals · 2025Article
- Aggravating effect of abnormal low-density protein cholesterol level on coronary atherosclerotic plaque in type 2 diabetes mellitus patients assessed by coronary computed tomography angiography.Cardiovascular diabetology · 2024Article
- Relationship between Indices of Vascular Function and Presence of Overt Cardiovascular Disease among Persons with Poorly Controlled Type 2 Diabetes.Journal of cardiovascular development and disease · 2021Article
- Effects of Different Antidiabetic Medications on Endothelial Glycocalyx, Myocardial Function, and Vascular Function in Type 2 Diabetic Patients: One Year Follow-Up Study.Journal of clinical medicine · 2019Article
- Myocardial perfusion in patients with non-ischaemic systolic heart failure and type 2 diabetes: a cross-sectional study using Rubidium-82 PET/CT.The international journal of cardiovascular imaging · 2018Article
- Lipoprotein ratios are better than conventional lipid parameters in predicting arterial stiffness in young men.Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
- Visceral Adiposity is Preferentially Associated with Vascular Stiffness Rather than Thickness in Men with Type 2 Diabetes.Journal of atherosclerosis and thrombosis · 2016Article
- Prognostic value of coronary computed tomography angiography in diabetic patients without chest pain syndrome.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Serum leptin levels are independently related to the incidence of ischemic heart disease in a prospective study of patients with type 2 diabetes.Cardiovascular diabetology · 2015Article
- A prospective observational study of all-cause mortality in relation to serum 25-OH vitamin D3 and parathyroid hormone levels in patients with type 2 diabetes.Diabetology & metabolic syndrome · 2015Article
- Review
- Cardiovascular microRNAs: as modulators and diagnostic biomarkers of diabetic heart disease.Cardiovascular diabetology · 2014Review
- Chronic Mild Hyperglycemia in GCK-MODY Patients Does Not Increase Carotid Intima-Media Thickness.International journal of endocrinology · 2013Article
- Value of exercise tolerance testing in evaluation of diabetic patients presented with atypical chest discomfort.International journal of endocrinology and metabolism · 2013Article
- Determinants of brachial-ankle pulse wave velocity in normotensive young adults with type 2 diabetes mellitus.Journal of Korean medical science · 2012Article
- The distinctive nature of atherosclerotic vascular disease in diabetes: pathophysiological and morphological insights.Current diabetes reports · 2012Review
- New insights into insulin resistance in the diabetic heart.Trends in endocrinology and metabolism: TEM · 2011Review
- Exercise treadmill test in detecting asymptomatic coronary artery disease in type 2 diabetes mellitus.Diabetes & metabolism journal · 2011Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular disease is the major cause of mortality in type 2 diabetes mellitus. The criteria for the selection of those asymptomatic patients with type 2 diabetes who should undergo cardiac screening and the therapeutic consequences of screening remain controversial. Non-invasive techniques as markers of atherosclerosis and myocardial ischaemia may aid risk stratification and the implementation of tailored therapy for the patient with type 2 diabetes. In the present article we review the literature on the implementation of non-invasive vascular tools and cardiac imaging techniques in this patient group. The value of these techniques as endpoints in clinical trials and as risk estimators in asymptomatic diabetic patients is discussed. Carotid intima-media thickness, arterial stiffness and flow-mediated dilation are abnormal long before the onset of type 2 diabetes. These vascular tools are therefore most likely to be useful for the identification of 'at risk' patients during the early stages of atherosclerotic disease. The additional value of these tools in risk stratification and tailored therapy in type 2 diabetes remains to be proven. Cardiac imaging techniques are more justified in individuals with a strong clinical suspicion of advanced coronary heart disease (CHD). Asymptomatic myocardial ischaemia can be detected by stress echocardiography and myocardial perfusion imaging. The more recently developed non-invasive multi-slice computed tomography angiography is recommended for exclusion of CHD, and can therefore be used to screen asymptomatic patients with type 2 diabetes, but has the associated disadvantages of high radiation exposure and costs. Therefore, we propose an algorithm for the screening of asymptomatic diabetic patients, the first step of which consists of coronary artery calcium score assessment and exercise ECG.
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