Th17 and cancer: friends or foes?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. The role of acupoint stimulation as an adjunct therapy for lung cancer: a systematic review and meta-analysis.BMC complementary and alternative medicine · 2013
   Pooled it
2. Microbiota-Derived Proteins Shape T Cell Responses in Healthy and Colorectal Cancer Subjects.Biomedicines · 2026
   Article
3. An mRNA lipid nanoparticle-incorporated nanofiber-hydrogel composite for cancer immunotherapy.Nature communications · 2025
   Article
4. The RNA binding protein CARHSP1 facilitates tumor growth, metastasis and immune escape by enhancing IL-17RA mRNA stabilization in prostate cancer.Cell & bioscience · 2025
   Article
5. T cells in health and disease.Signal transduction and targeted therapy · 2023
   Review
6. Nanoparticle Interactions with the Tumor Microenvironment.Bioconjugate chemistry · 2019
   Review
7. Interleukin 17 is a chief orchestrator of immunity.Nature immunology · 2017
   Review
8. Role of IL-17 in Glioma Progression.Journal of spine & neurosurgery · 2013
   Article
9. High expression of IL-17 and IL-17RE associate with poor prognosis of hepatocellular carcinoma.Journal of experimental & clinical cancer research : CR · 2013
   Article
10. Generation and immunologic functions of Th17 cells in malignant gliomas.Cancer immunology, immunotherapy : CII · 2013
    Article
11. The tyrosine phosphatase SHP-1 dampens murine Th17 development.Blood · 2012
    Article
12. IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma.Molecular cancer · 2011
    Article
13. IFN-γ, IL-17 and TGF-β involvement in shaping the tumor microenvironment: The significance of modulating such cytokines in treating malignant solid tumors.Cancer cell international · 2011
    Article
14. Human Th17 cells can be induced through head and neck cancer and have a functional impact on HNSCC development.British journal of cancer · 2010
    Article
15. T(H)17 cells in tumour immunity and immunotherapy.Nature reviews. Immunology · 2010
    Review
16. T cell-tumor interaction directs the development of immunotherapies in head and neck cancer.Clinical & developmental immunology · 2010
    Review
17. Type 17 CD8+ T cells display enhanced antitumor immunity.Blood · 2009
    Article
18. Tumor-induced suppression of CTL expansion and subjugation by gp96-Ig vaccination.Cancer research · 2009
    Article
19. Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans.Immunological reviews · 2008
    Review

Corrections and comments

• Comment on
  Tumor-specific Th17-polarized cells eradicate large established melanoma.2008

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.