Evidence map›Paper›PMID 18606227›Full record

ReviewCurrent opinion in structural biology2008

Protein dynamics from time resolved UV Raman spectroscopy.

Gurusamy Balakrishnan, Colin L Weeks, Mohammed Ibrahim, Alexandra V Soldatova, Thomas G Spiro

Abstract readReview
In one paragraph

Review in Current opinion in structural biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Wanted: more monitoring and control during inclusion body processing.World journal of microbiology & biotechnology · 2018
    Review
  5. Article
  6. Hydrogen bonds are a primary driving force for de novo protein folding.Acta crystallographica. Section D, Structural biology · 2017
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Raman studies of solution polyglycine conformations.The journal of physical chemistry. B · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gurusamy BalakrishnanDepartment of Chemistry, University of Washington, Seattle, WA 98195, United States.
Colin L Weeks
Mohammed Ibrahim
Alexandra V Soldatova
Thomas G Spiro
University of Washington · US

Funding

ULTRAVIOLET RAMAN STUDIES OF PROTEINS AND NUCLEIC ACIDSR01GM025158 · NIGMS · UNIVERSITY OF WASHINGTON · PI SPIRO, THOMAS G. · 1985 to 2014
$5.1M
HEME PROTEIN STRUCTURE AND DYNAMICSR01GM033576 · NIGMS · UNIVERSITY OF WASHINGTON · PI SPIRO, THOMAS G. · 1985 to 2010
$3.5M
ASYMMETRIC HYDROCARBOXYLATION OF PROCHIRAL OLEFINSF32GM012526 · NIGMS · HARVARD UNIVERSITY · PI SHEPPARD, GEORGE S · 1988 to 1989
–
NIGMS NIH HHS GM12526NIGMS NIH HHS R01 GM025158NIGMS NIH HHS R01 GM033576
6 · The paper itself

Abstract

Raman spectroscopy can provide unique information on the evolution of structure in proteins over a wide range of time scales; the picosecond to millisecond range can be accessed with pump-probe techniques. Specific parts of the molecule are interrogated by tuning the probe laser to a resonant electronic transition, including the UV transitions of aromatic residues and of the peptide bond. Advances in laser technology have enabled the characterization of transient species at an unprecedented level of structural detail. Applications to protein unfolding and allostery are reviewed.

Indexed as

Models, MolecularProtein ConformationProtein DenaturationProtein FoldingProteinsScattering, RadiationSensitivity and SpecificitySpectrum Analysis, RamanThermodynamicsUltraviolet RaysProteins

Identifiers

PMID18606227
PMCPMC2583231
OpenAlexW1977369837

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.