ReviewCurrent allergy and asthma reports2008
Airway wall remodeling in asthma: from the epithelial layer to the adventitia.
Review in Current allergy and asthma reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Steroid-independent upregulation of matrix metalloproteinase 9 in chronic rhinosinusitis patients with radiographic evidence of osteitis.International forum of allergy & rhinology · 2013Trial
- Gene Therapy for Immunoglobulin E, Complement-Mediated, and Eosinophilic Disorders.Human gene therapy · 2023Review
- Reduced biomechanical models for precision-cut lung-slice stretching experiments.Journal of mathematical biology · 2021Article
- The importance of reporting house dust mite endotoxin abundance: impact on the lung transcriptome.American journal of physiology. Lung cellular and molecular physiology · 2020Article
- Tripterine alleviates lipopolysaccharide-induced airway epithelial barrier dysfunction through suppressing the Hippo pathway.RSC advances · 2018Article
- Posttranscriptional Regulation of Interleukin-33 Expression by MicroRNA-200 in Bronchial Asthma.Molecular therapy : the journal of the American Society of Gene Therapy · 2018Article
- TGF-β1 Signaling and Tissue Fibrosis.Cold Spring Harbor perspectives in biology · 2018Review
- New targets for resolution of airway remodeling in obstructive lung diseases.F1000Research · 2018Review
- Alteration in Claudin-4 Contributes to Airway Inflammation and Responsiveness in Asthma.Allergy, asthma & immunology research · 2018Article
- Nasal administration of interleukin-33 induces airways angiogenesis and expression of multiple angiogenic factors in a murine asthma surrogate.Immunology · 2016Article
- Potential of Inducible Nitric Oxide Synthase as a Therapeutic Target for Allergen-Induced Airway Hyperresponsiveness: A Critical Connection to Nitric Oxide Levels and PARP Activity.Mediators of inflammation · 2016Article
- Animal models of allergic airways disease: where are we and where to next?Journal of cellular biochemistry · 2014Review
- Urinary bladder, cystitis and nerve/urothelial interactions.Autonomic neuroscience : basic & clinical · 2014Review
- MicroRNAs: new insights into chronic childhood diseases.BioMed research international · 2013Review
- Correlation of hyaluronan deposition with infiltration of eosinophils and lymphocytes in a cockroach-induced murine model of asthma.Glycobiology · 2013Article
- Nervous network for lower urinary tract function.International journal of urology : official journal of the Japanese Urological Association · 2013Review
- MicroRNA Regulation of Smooth Muscle Phenotype.Molecular and cellular pharmacology · 2012Article
- Investigating in vivo airway wall mechanics during tidal breathing with optical coherence tomography.Journal of biomedical optics · 2011Article
- Cystitis, co-morbid disorders and associated epithelial dysfunction.Neurourology and urodynamics · 2011Review
- Hyaluronan deposition and correlation with inflammation in a murine ovalbumin model of asthma.Matrix biology : journal of the International Society for Matrix Biology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is an episodic respiratory syndrome caused by several pathogenic processes. This recurrent syndrome is associated with an accelerated decline in lung function and increase in airway obstruction over time. The reduced lung function is a consequence of tissue restructuring of all the components of the airway wall: 1) epithelium metaplasia; 2) altered quantity, composition, and distribution of extracellular matrix components; 3) microvascular remodeling; and 4) increase of airway smooth muscle mass. How these structural changes affect lung functions is not entirely clear. Deeper understandings of the altered structure and related functional impairment are important for gaining insights into the mechanisms underlying asthma. This review describes the tissue remodeling observed in different compartments of the asthmatic airway wall, from the airway lumen to adventitia. The underlying mechanisms driving the remodeling processes are also briefly reviewed.
Indexed as
Identifiers
18606090What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.