ReviewReviews in endocrine & metabolic disorders2008
Pediatric vitamin D and calcium nutrition in developing countries.
Review in Reviews in endocrine & metabolic disorders, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Genetic predisposition to increased serum calcium, bone mineral density, and fracture risk in individuals with normal calcium levels: mendelian randomisation study.BMJ (Clinical research ed.) · 2019Pooled it
- Trial
- The plasma proteome identifies expected and novel proteins correlated with micronutrient status in undernourished Nepalese children.The Journal of nutrition · 2013Trial
- Article
- Nutritional status of children under-five in rural mozambique: the role of phytate intake and mineral bioavailability.Journal of health, population, and nutrition · 2026Article
- Long-term epidemiological insights into rickets: a nationwide population-based retrospective study.Clinical and experimental pediatrics · 2025Article
- Association between dyslipidemia and vitamin D deficiency: a cross-sectional study in Chinese healthy population.Frontiers in endocrinology · 2025Article
- Article
- Effectiveness of Vitamin D and Alpha-Lipoic Acid in COVID-19 Infection: A Literature Review.Cureus · 2024Review
- Hereditary vitamin D resistant rickets (HVDRR) case series: phenotype, genotype, conventional treatment, and adjunctive cinacalcet therapy.Pediatric endocrinology, diabetes, and metabolism · 2024Article
- Developing feasible healthy diets for Ethiopian women of reproductive age: a linear goal programming approach.Public health nutrition · 2023Article
- Vitamin DLife (Basel, Switzerland) · 2023Article
- The Role of Vitamin D in the Relationship Between Gender and Deep Vein Thrombosis Among Stroke Patients.Frontiers in nutrition · 2021Article
- Measurement of Bone Mineral Density in Children with Cerebral Palsy from an Ethical Issue to a Diagnostic Necessity.BioMed research international · 2020Article
- Article
- Article
- Immunomodulatory Effect of Vitamin D and Its Potential Role in the Prevention and Treatment of Type 1 Diabetes Mellitus-A Narrative Review.Molecules (Basel, Switzerland) · 2018Review
- The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention.Reviews in endocrine & metabolic disorders · 2017Review
- Vitamin D deficiency among smear positive pulmonary tuberculosis patients and their tuberculosis negative household contacts in Northwest Ethiopia: a case-control study.Annals of clinical microbiology and antimicrobials · 2017Article
- Preventable but neglected: rickets in an informal settlement, Nairobi, Kenya.Public health action · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over one billion humans have insufficient circulating levels of vitamin D, and dietary insufficiency of calcium is common in developing countries. Worldwide, nutritional rickets is considered to be the most common non-communicable disease of children. Rickets can be due either to primary deficiencies of vitamin D or calcium or to combined deficiencies of both elements. Vitamin D deficiency is also increasingly linked to non-skeletal complications. Even without laboratory and radiologic resources, the diagnosis of rickets is considered clinically when a child presents with limb deformities and has beaded ribs and widened wrists and ankles. Prevention is possible through increased sun exposure and dietary enhancement. Treatment of nutritional rickets involves provision of adequate vitamin D and calcium. Further research is needed to elucidate the precise epidemiology of vitamin D and calcium deficiencies in developing countries, to determine the roles of additional pathologic factors contributing to the development and morbidity of rickets, to improve affordable and feasible means of diagnosing rickets in resource-limited areas, to better target at-risk populations for preventive interventions, to identify accurate dosing and delivery of therapeutic interventions, and to evaluate the long-term consequences of vitamin D and calcium deficiencies in childhood.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.