ArticleEuropean journal of pediatrics2008
Splenic infarction in a patient hereditary spherocytosis, protein C deficiency and acute infectious mononucleosis.
Article in European journal of pediatrics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Serial computed tomography imaging of splenic infarction associated with Epstein-Barr virus infection.IDCases · 2025Article
- Article
- Splenic Infarction Associated With Epstein-Barr Virus in an Adult With an Anatomic Anomaly: A Case Report.Cureus · 2023Article
- Article
- Splenic infarction after Epstein-Barr virus infection in a patient with hereditary spherocytosis: a case report and literature review.BMC surgery · 2022Review
- Case Report: Splenic Infarction in Infectious Mononucleosis due to Epstein-Barr Virus Infection.The American journal of tropical medicine and hygiene · 2021Article
- Multiple splenic infarcts: unusual presentation of hereditary spherocytosis associated with acute Epstein-Barr virus infection.BMJ case reports · 2020Article
- Ultrasonography of the pediatric spleen: a pictorial essay.Journal of ultrasound · 2019Review
- Splenic infarct in a patient with Infectious Mononucleosis: a rare presentation.Journal of community hospital internal medicine perspectives · 2017Article
- The unexpected finding of a splenic infarction in a patient with infectious mononucleosis due to Epstein-Barr virus.BMJ case reports · 2015Article
- An adolescent with hereditary spherocytosis who presented with splenic infarction.BMJ case reports · 2015Review
- Splenic infarction, warm autoimmune hemolytic anemia and antiphospholipid antibodies in a patient with infectious mononucleosis.International journal of hematology · 2012Article
- Splenic infarction in a patient with autoimmune hemolytic anemia and protein C deficiency.The Korean journal of hematology · 2011Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Splenic infarction is a common cause of left upper quadrant pain and must be suspected in patients with hematologic or thromboembolic conditions and signs of localized or systemic inflammation. Although several mechanisms have been proposed for splenic infarction in patients with various hematologic disorders, hereditary spherocytosis (HS) is usually not associated with an increased risk for thromboembolic events. We report a 13-year-old male with HS who was referred to our hospital with a 4-day history of fever and left upper quadrant pain. Ultrasound scans and magnetic resonance imaging showed lesions suggestive of splenic infarction. Initially, antibiotic treatment was started because secondary infection was suspected. However, 1 week after admission the patient developed typical clinical signs of acute infectious mononucleosis. Further laboratory work up confirmed the diagnosis of acute Epstein-Barr virus infection and additionally revealed protein C deficiency. This association has not been reported previously and may have contributed to the development of splenic infarction. Since infectious mononucleosis is a common cause for clinical consultations in adolescence, physicians caring for children with hematologic disorders should be particularly aware of those possible complications.
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