ArticleActa biochimica et biophysica Sinica2008
Wnt signaling: the good and the bad.
Article in Acta biochimica et biophysica Sinica, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- The Wnt/β-catenin-P2-HNF4α feedback loop facilitates colorectal tumorigenesis and malignancy.Journal of translational medicine · 2025Article
- Resveratrol Mediated Regulation of Hippocampal Neuroregenerative Plasticity via SIRT1 Pathway in Synergy with Wnt Signaling: Neurotherapeutic Implications to Mitigate Memory Loss in Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2023Review
- Wnt signaling in liver regeneration, disease, and cancer.Clinical and molecular hepatology · 2023Review
- The functional roles of the circRNA/Wnt axis in cancer.Molecular cancer · 2022Review
- Article
- Inhibition of WNT7A-β-catenin signaling pathway sensitizes oral squamous cell carcinoma to cisplatin.International journal of clinical and experimental pathology · 2018Article
- The role of Wnt regulation in heart development, cardiac repair and disease: A tissue engineering perspective.Biochemical and biophysical research communications · 2016Review
- Activating mutations in CTNNB1 in aldosterone producing adenomas.Scientific reports · 2016Article
- Components of the canonical and non-canonical Wnt pathways are not mis-expressed in pituitary tumors.PloS one · 2013Article
- Wnt Signaling in Neurogenesis during Aging and Physical Activity.Brain sciences · 2012Article
- Peripheral T-lymphocytes express WNT7A and its restoration in leukemia-derived lymphoblasts inhibits cell proliferation.BMC cancer · 2012Article
- Article
- An ordered EST catalogue and gene expression profiles of cassava (Manihot esculenta) at key growth stages.Plant molecular biology · 2010Article
- Dynamic expression of a LEF-EGFP Wnt reporter in mouse development and cancer.Genesis (New York, N.Y. : 2000) · 2010Article
- The F-box protein beta-TrCp1/Fbw1a interacts with p300 to enhance beta-catenin transcriptional activity.The Journal of biological chemistry · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Since the first Wnt gene was identified in 1982, the functions and mechanisms of Wnt signaling have been extensively studied. Wnt signaling is conserved from invertebrates to vertebrates and regulates early embryonic development as well as the homeostasis of adult tissues. In addition, both embryonic stem cells and adult stem cells are regulated by Wnt signaling. Deregulation of Wnt signaling is associated with many human diseases, particularly cancers. In this review, we will discuss in detail the functions of many components involved in the Wnt signal transduction pathway. Then, we will explore what is known about the role of Wnt signaling in stem cells and cancers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.