ReviewCurrent opinion in cell biology2008
Temporal and spatial regulation of integrins during development.
Review in Current opinion in cell biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 58 citations in OpenAlex.
- Laminin α5 and integrins α3 and α6 coordinately regulate collective cell migration in vivo.Development (Cambridge, England) · 2026Article
- Mechanobiological engineering strategies for organoid culture.APL bioengineering · 2025Review
- Getting there in one piece: The Rac pathway prevents cell fragmentation in a nonprotrusively migrating leader cell during organogenesis.bioRxiv : the preprint server for biology · 2023Article
- Integrin signaling in cancer: bidirectional mechanisms and therapeutic opportunities.Cell communication and signaling : CCS · 2023Review
- Roles of Endocytic Processes and Early Endosomes on Focal Adhesion Dynamics in MDA-MB-231 Cells.Reports of biochemistry & molecular biology · 2021Article
- Integrin trafficking in cells and tissues.Nature cell biology · 2019Review
- Design Principles for Pluripotent Stem Cell-Derived Organoid Engineering.Stem cells international · 2019Review
- Mechanical Forces Reshape Differentiation Cues That Guide Cardiomyogenesis.Circulation research · 2016Review
- Research advances on structure and biological functions of integrins.SpringerPlus · 2016Review
- TGFβ signaling promotes matrix assembly during mechanosensitive embryonic salivary gland restoration.Matrix biology : journal of the International Society for Matrix Biology · 2015Article
- Extracellular-matrix-based and Arg-Gly-Asp-modified photopolymerizing hydrogels for cartilage tissue engineering.Tissue engineering. Part A · 2015Article
- Metastasis review: from bench to bedside.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Review
- The primitive endoderm segregates from the epiblast in β1 integrin-deficient early mouse embryos.Molecular and cellular biology · 2014Article
- Long intergenic non-coding RNA HOTAIRM1 regulates cell cycle progression during myeloid maturation in NB4 human promyelocytic leukemia cells.RNA biology · 2014Article
- Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.Cell death and differentiation · 2013Article
- Genetic signatures shared in embryonic liver development and liver cancer define prognostically relevant subgroups in HCC.Molecular cancer · 2012Article
- Overview: studying integrins in vivo.Methods in molecular biology (Clifton, N.J.) · 2012Review
- Turnover of focal adhesions and cancer cell migration.International journal of cell biology · 2012Article
- Extracellular matrix in development: insights from mechanisms conserved between invertebrates and vertebrates.Cold Spring Harbor perspectives in biology · 2011Review
- ZF21 protein, a regulator of the disassembly of focal adhesions and cancer metastasis, contains a novel noncanonical pleckstrin homology domain.The Journal of biological chemistry · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Integrin receptors for extracellular matrix (ECM) are critical determinants of biological processes. Regulation of integrin expression is one way for cells to respond to changes in the ECM, to integrate intracellular signals, and to obtain appropriate adhesion for cell motility, proliferation, and differentiation. Transcriptional and post-translational mechanisms for changing the integrin repertoire at the cell surface have recently been described. These mechanisms work through transcriptional regulation that alters the proportions of one integrin relative to another, referred to as integrin switching, or through localized regulation of integrin-ECM interactions, thus providing exquisite control over cell rearrangements during tissue morphogenesis and remodeling. These integrin regulatory pathways may also be important targets in such emerging fields as tissue engineering and regenerative medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.