Evidence map›Paper›PMID 18601997›Full record

ArticleGenomics2008

A high-resolution radiation hybrid map of rhesus macaque chromosome 5 identifies rearrangements in the genome assembly.

Genesio M Karere, Lutz Froenicke, Lee Millon, James E Womack, Leslie A Lyons

Open access · greenAbstract read
In one paragraph

Article in Genomics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Genesio M KarereDepartment of Population Health and Reproduction, School of Veterinary Medicine, California National Primate Research Center, Davis, CA 95616, USA.
Lutz Froenicke
Lee Millon
James E Womack
Leslie A Lyons
Texas A&M University · USUniversity of California, Davis · US

Funding

GENETIC RESOURCES FOR NON-HUMAN PRIMATESR24RR017584 · NCRR · UNIVERSITY OF CALIFORNIA DAVIS · PI LYONS, LESLIE A · 2003 to 2007
$1.3M
NCRR NIH HHS R24 RR017584
6 · The paper itself

Abstract

A 10,000-rad radiation hybrid (RH) cell panel of the rhesus macaque was generated to construct a comprehensive RH map of chromosome 5. The map represents 218 markers typed in 185 RH clones. The 4846-cR map has an average marker spacing of 798 kb. Alignments of the RH map to macaque and human genome sequences confirm a large inversion and reveal a previously unreported telomeric inversion. The macaque genome sequence indicates small translocations from the ancestral homolog of macaque chromosome 5 to macaque chromosomes 1 and 6. The RH map suggests that these are probably assembly artifacts. Unlike the genome sequence, the RH mapping data indicate the conservation of synteny between macaque chromosome 5 and human chromosome 4. This study shows that the 10,000-rad panel is appropriate for the generation of a high-resolution whole-genome RH map suitable for the verification of the rhesus genome assembly.

Indexed as

Radiation, IonizingAnimalsCells, CulturedChromosome AberrationsChromosome MappingChromosomes, MammalianHumansMacaca mulattaMale

Identifiers

PMID18601997
PMCPMC2605074
OpenAlexW2019338524

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.