ArticleDigestive diseases and sciences2009
The effect of gastroesophageal flap valve appearance on the management of patients with symptoms of gastroesophageal reflux disease.
Article in Digestive diseases and sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- What is the significance of the Hill classification?Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023Article
- Abnormal Gastroesophageal Flap Valve Is Associated With High Gastresophageal Reflux Disease Questionnaire Score and the Severity of Gastroesophageal Reflux Disease in Vietnamese Patients With Upper Gastrointestinal Symptoms.Journal of neurogastroenterology and motility · 2018Article
- Gastroesophageal flap valve reflected EGJ morphology and correlated to acid reflux.BMC gastroenterology · 2017Article
- Clinical Characteristics of Severe Erosive Esophagitis among Patients with Erosive Esophagitis: A Case-control Study.Internal medicine (Tokyo, Japan) · 2017Article
- Impacts of endoscopic gastroesophageal flap valve grading on pediatric gastroesophageal reflux disease.PloS one · 2014Article
- Correlation of the gastroesophageal flap valve grade with the surgery rate in patients with gastroesophageal reflux disease.Surgical endoscopy · 2013Article
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Authors and funding
6 authors.
Funding
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Abstract
purposeTo assess the effectiveness of anti-reflux treatment in gastroesophageal reflux disease patients classified according to esophagogastric junction morphology (Hill classification).
resultsA symptom score and endoscopic grading of gastrooesophageal flap valve appearance were determined in 49 symptomatic patients (female 26, male 23; mean age 49 years, range 21-76 years). Patients received 8 weeks of continuous rabeprazole at a daily dose of 20 mg and, upon symptom control, continued with on-demand treatment for 3 months. The mean symptom score at 8 weeks was significantly reduced in all groups. However, at the end of the on-demand therapy, patients with Hill grade IV had used more rabeprazole tablets than those in the two other groups (II: 10.86 +/- 14.52, III: 14.73 +/- 14.58, IV: 25.78 +/- 15.85; P = 0.002).
conclusionsContinuous treatment is effective in all groups of patients with reflux disease. Grading patients according to the gastroesophageal flap valve appearance is useful as a prognostic factor, especially when on-demand therapy is considered to be an option.
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