Evidence map›Paper›PMID 18600227›Full record

ArticleNature protocols2008

3DNA: a versatile, integrated software system for the analysis, rebuilding and visualization of three-dimensional nucleic-acid structures.

Xiang-Jun Lu, Wilma K Olson

Abstract read
In one paragraph

Article in Nature protocols, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 347 papers.

0numbers the graph read from it
0cells of the map it votes in
347citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

347 citing papers in PubMed.

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  14. Enhanced i-Motif Stability through Consecutive 2',2'-Difluorocytidine Incorporation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. The Effect of 2'F-RNA on I-Motif Structure and Stability.Molecules (Basel, Switzerland) · 2025
    Article
  19. Article
  20. Interfacing B-DNA and DNA Mimic Foldamers.Angewandte Chemie (International ed. in English) · 2025
    Article

287 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xiang-Jun LuDepartment of Chemistry and Chemical Biology and BioMaPS Institute for Quantitative Biology, Rutgers-The State University of New Jersey, Piscataway, New Jersey 08854-8087, USA. 3dna.lu@gmail.com
Wilma K Olson

Funding

NUCLEIC ACID CONFORMATION, PROPERTIES, AND INTERACTIONSR01GM020861 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI OLSON, WILMA K · 1985 to 2006
$1.6M
NUCLEIC ACID CONFORMATION, PROPERTIES, &INTERACTIONSR37GM020861 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI OLSON, WILMA K · 1988 to 1997
–
NIGMS NIH HHS GM20861NIGMS NIH HHS R01 GM020861
6 · The paper itself

Abstract

We present a set of protocols showing how to use the 3DNA suite of programs to analyze, rebuild and visualize three-dimensional nucleic-acid structures. The software determines a wide range of conformational parameters, including the identities and rigid-body parameters of interacting bases and base-pair steps, the nucleotides comprising helical fragments, the area of overlap of stacked bases and so on. The reconstruction of three-dimensional structure takes advantage of rigorously defined rigid-body parameters, producing rectangular block representations of the nucleic-acid bases and base pairs and all-atom models with approximate sugar-phosphate backbones. The visualization components create vector-based drawings and scenes that can be rendered as raster-graphics images, allowing for easy generation of publication-quality figures. The utility programs use geometric variables to control the view and scale of an object, for comparison of related structures. The commands run in seconds even for large structures. The software and related information are available at http://3dna.rutgers.edu/.

Indexed as

Models, MolecularNucleic Acid ConformationSoftwareNucleic AcidsNucleic Acids

Identifiers

PMID18600227
PMCPMC3065354

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.