ArticleBiosensors & bioelectronics2008
Detection of human proteins using arrayed imaging reflectometry.
Article in Biosensors & bioelectronics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Emerging nanophotonic biosensor technologies for virus detection.Nanophotonics (Berlin, Germany) · 2022Review
- Immunosensor-based label-free and multiplex detection of influenza viruses: State of the art.Biosensors & bioelectronics · 2019Review
- Functionalized Polymer Microgel Particles Enable Customizable Production of Label-Free Sensor Arrays.Analytical chemistry · 2015Article
- Article
- Examining the interactions of the splicing factor MBNL1 with target RNA sequences via a label-free, multiplex method.Analytical chemistry · 2014Article
- Validation of arrayed imaging reflectometry biosensor response for protein-antibody interactions: cross-correlation of theory, experiment, and complementary techniques.Analytical chemistry · 2011Article
- Analysis of inflammatory biomarkers by Arrayed Imaging Reflectometry.Biosensors & bioelectronics · 2011Article
- Prostate specific antigen detection in patient sera by fluorescence-free BioCD protein array.Biosensors & bioelectronics · 2011Article
- Ambient molecular water accumulation on silica surfaces detected by a reflectance interference optical balance.Applied physics letters · 2010Article
- Label-free detection techniques for protein microarrays: prospects, merits and challenges.Proteomics · 2010Review
- Label-free technologies for quantitative multiparameter biological analysis.Analytical and bioanalytical chemistry · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Assays built upon protein arrays are critical tools in determining the basic nature of biology, and have considerable promise in diagnosing human disease. These protein arrays aid in the elucidation of mapping pathway interactions, disease biomarker discovery, and regulatory processes. The solutions used in these experiments, including cellular lysate and serum, are inherently complex mixtures and are high in total protein content. Therefore, array-based assays must be robust and maintain a high level of selectivity and sensitivity. We report herein that arrayed imaging reflectometry (AIR), a label-free biosensing platform we have previously disclosed, is highly suitable for the detection of human proteins in complex solutions. In particular, we demonstrate array-based detection of cytokines in buffered solutions, and in undiluted human serum.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.