Evidence map›Paper›PMID 18598630›Full record

ArticleEmerging infectious diseases2008

A prospective study of etiology of childhood acute bacterial meningitis, Turkey.

Mehmet Ceyhan, Inci Yildirim, Paul Balmer, Ray Borrow, Bunyamin Dikici, Mehmet Turgut, Nese Kurt, Aysel Aydogan, Cigdem Ecevit, Yasar Anlar and 14 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.

  1. Pooled it
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  6. Prevalence of InvasiveIranian journal of public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 11 institutions in 2 countries.

Mehmet CeyhanHacettepe University, Ankara, Turkey.
Inci Yildirim
Paul Balmer
Ray Borrow
Bunyamin Dikici
Mehmet Turgut
Nese Kurt
Aysel Aydogan
Cigdem Ecevit
Yasar Anlar
Ozlem Gulumser
Gonul Tanir
Nuran Salman
Nezahat Gurler
Nevin Hatipoglu
Mustafa Hacimustafaoglu
Solmaz Celebi
Yavuz Coskun
Emre Alhan
Umit Celik
Yildiz Camcioglu
Gulten Secmeer
Deniz Gur
Steve Gray
Istanbul University · TRHacettepe University · TRBursa Uludağ Üni̇versi̇tesi̇ · TRCukurova University · TRDr. Behçet Uz Çocuk Hastalıkları Hastanesi · TRFırat University · TROndokuz Mayıs University · TRAnkara (Czechia) · CZDicle University · TRDr Sami Ulus Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi · TRGaziantep University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Determination of the etiology of bacterial meningitis and estimating cost of disease are important in guiding vaccination policies. To determine the incidence and etiology of meningitis in Turkey, cerebrospinal fluid (CSF) samples were obtained prospectively from children (1 month-17 years of age) with a clinical diagnosis of acute bacterial meningitis. Multiplex PCR was used to detect DNA evidence of Streptococcus pneumoniae, Haemophilus influenzae type b (Hib), and Neisseria meningitidis. In total, 408 CSF samples were collected, and bacterial etiology was determined in 243 cases; N. meningitidis was detected in 56.5%, S. pneumoniae in 22.5%, and Hib in 20.5% of the PCR-positive samples. Among N. meningitidis-positive CSF samples, 42.7%, 31.1%, 2.2%, and 0.7% belonged to serogroups W-135, B, Y, and A, respectively. This study highlights the emergence of serogroup W-135 disease in Turkey and concludes that vaccines to prevent meningococcal disease in this region must provide reliable protection against this serogroup.

Indexed as

AdolescentChildChild, PreschoolFemaleHaemophilus influenzae type bHumansIncidenceInfantMaleMeningitis, BacterialMolecular EpidemiologyNeisseria meningitidisPopulation SurveillanceProspective StudiesStreptococcus pneumoniaeTurkey

Identifiers

PMID18598630
PMCPMC2600347
OpenAlexW2100879448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.