Evidence map›Paper›PMID 18598387›Full record

ReviewJournal of biology2008

Making the jump: new insights into the mechanism of trans-translation.

Jacek Wower, Iwona K Wower, Christian Zwieb

Open access · goldAbstract readReview
In one paragraph

Review in Journal of biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jacek WowerDepartment of Animal Sciences, Auburn University, Auburn, AL 36849, USA. zwieb@uthct.edu
Iwona K Wower
Christian Zwieb
Auburn University · USThe University of Texas Health Science Center at Tyler · US

Funding

STRUCTURE/FUNCTION OF SRP RNAR01GM049034 · NIGMS · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI ZWIEB, CHRISTIAN WOLFGANG · 1995 to 2006
$1.2M
STRUCTURE/FUNCTION OF TMRNAR01GM058267 · NIGMS · AUBURN UNIVERSITY AT AUBURN · PI WOWER, JACEK · 1998 to 2003
$720k
NIGMS NIH HHS GM49034NIGMS NIH HHS GM58267NIGMS NIH HHS R01 GM049034NIGMS NIH HHS R01 GM058267
6 · The paper itself

Abstract

The transfer-messenger ribonucleoprotein (tmRNP), which is composed of RNA and a small protein, small protein B (SmpB), recycles ribosomes that are stalled on broken mRNAs lacking stop codons and tags the partially translated proteins for degradation. Although it is not yet understood how the ribosome gets from the 3' end of the truncated message onto the messenger portion of the tmRNA to add the tag, a recent study in BMC Biology has shed some light on this astonishing feat.

Indexed as

Protein BiosynthesisProtein ConformationRibosomesRNA, BacterialTemplates, GeneticRNA, BacterialtmRNA

Identifiers

PMID18598387
PMCPMC2447533
OpenAlexW2095874517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.