Evidence map›Paper›PMID 18598378›Full record

ReviewGenome biology2008

What makes pathogens pathogenic.

Garth D Ehrlich, N Luisa Hiller, Fen Ze Hu

Abstract readReview
In one paragraph

Review in Genome biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. ThemBio · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. A new lexicon in the age of microbiome research.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  8. Insights into theAntibiotics (Basel, Switzerland) · 2022
    Article
  9. Review
  10. Article
  11. Wildlife Waterfowl as a Source of PathogenicPathogens (Basel, Switzerland) · 2022
    Article
  12. Frontiers in microbiology · 2022
    Article
  13. Review
  14. Species-Level Profiling ofGenetic testing and molecular biomarkers · 2021
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Garth D EhrlichCenter for Genomic Sciences, Allegheny General Hospital, Allegheny Singer Research Institute, Pittsburgh, PA 15212, USA. gehrlich@wpahs.org
N Luisa Hiller
Fen Ze Hu

Funding

THE ROLE OF BIOFILMS IN THE PATHOGENESIS OF OTORRHEAR01DC004173 · NIDCD · ALLEGHENY-SINGER RESEARCH INSTITUTE · PI EHRLICH, GARTH D. · 2000 to 2008
$7.0M
MOLECULAR ANALYSIS OF PATHOGENS IN OTITIS MEDIA BY PCRR01DC002148 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI EHRLICH, GARTH D. · 1994 to 2017
$6.5M
Pneumococcal Biofilms in Otitis MediaR01DC005659 · NIDCD · ALLEGHENY-SINGER RESEARCH INSTITUTE · PI POST, JAMES CHRISTOPHER · 2003 to 2007
$3.1M
NIDCD NIH HHS DC02148NIDCD NIH HHS DC04173NIDCD NIH HHS DC05659NIDCD NIH HHS R01 DC002148NIDCD NIH HHS R01 DC004173NIDCD NIH HHS R01 DC005659
6 · The paper itself

Abstract

Metazoans contain multiple complex microbial ecosystems in which the balance between host and microbe can be tipped from commensalism to pathogenicity. This transition is likely to depend both on the prevailing environmental conditions and on specific gene-gene interactions placed within the context of the entire ecosystem.

Indexed as

VirulenceAnimalsBacteriaHost-Pathogen InteractionsHumansMutation

Identifiers

PMID18598378
PMCPMC2481411

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.