ArticleMycopathologia2008
In vitro evaluation of putative virulence attributes of oral isolates of Candida spp. obtained from elderly healthy individuals.
Article in Mycopathologia, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 45 citations in OpenAlex.
- Host Age and Denture Wearing Jointly Contribute to Oral Colonization with Intrinsically Azole-Resistant Yeasts in the Elderly.Microorganisms · 2021Article
- Virulence Factors and Antifungal Susceptibility Profile ofJournal of fungi (Basel, Switzerland) · 2021Article
- Virulence of ClinicalPathogens (Basel, Switzerland) · 2021Article
- Evaluation of Antifungal Activity ofToxins · 2020Article
- Current Aspects in the Biology, Pathogeny, and Treatment ofInfection and drug resistance · 2020Review
- How much do we know about hemolytic capability of pathogenic Candida species?Folia microbiologica · 2018Review
- Virulence factors of fluconazole-susceptible and fluconazole-resistant Candida albicans after antimicrobial photodynamic therapy.Lasers in medical science · 2017Article
- Effects of human blood red cells on the haemolytic capability of clinical isolates of Candida tropicalis.Journal of biomedical science · 2015Article
- Antifungal activities of diphenyl diselenide alone and in combination with fluconazole or amphotericin B against Candida glabrata.Mycopathologia · 2013Article
- Insights into Candida tropicalis nosocomial infections and virulence factors.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012Review
- Epidemiological characteristics of Candida species colonizing oral and rectal sites of Jordanian infants.BMC pediatrics · 2011Article
- Investigating biofilm production, coagulase and hemolytic activity in Candida species isolated from denture stomatitis patients.The Eurasian journal of medicine · 2011Article
- Article
- Identification of Candida species isolated from bovine mastitic milk and their in vitro hemolytic activity in Western Turkey.Mycopathologia · 2010Article
- Examination of potential virulence factors of Candida tropicalis clinical isolates from hospitalized patients.Mycopathologia · 2010Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Identification of Candida isolates obtained from oral cavity of elderly healthy individuals revealed the predominance of non-albicans Candida species (88.9%) compared to Candida albicans (11%). CHROMagar Candida differential medium and PCR revealed the presence of Candida tropicalis (33.3%), Candida glabrata (27.8%), and Candida krusei (16.7%). We investigated the presence of virulence attributes in a total of 18 isolates, including acid protease and phospholipase production, hemolytic activity, and biofilm production. Extracellular protease was found in five isolates (27.8%) whereas extracellular phospholipase was found in three isolates (17%). All isolates showed hemolytic activity. About 56% of the isolates were weakly positive for biofilm formation (score +) whereas a minority (5.6%) of them showed strong biofilm formation (score 4+). Susceptibility in vitro of the isolates to fluconazole was carried out by microdilution method. Fluconazole showed a strong inhibition against most buccal isolates. The resistant isolates were 2 C. tropicalis, 2 C. glabrata, and 1 C. krusei.
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