ReviewEuropean journal of pediatrics2008
What's new in autism?
Review in European journal of pediatrics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 60 citations in OpenAlex.
- A double-blind placebo controlled trial of Ginkgo biloba added to risperidone in patients with autistic disorders.Child psychiatry and human development · 2012Trial
- Parental Beliefs and Feelings about Autism Spectrum Disorder in Iran.International journal of environmental research and public health · 2020Article
- The Prevalence of Insomnia and the Link between Iron Metabolism Genes Polymorphisms,International journal of environmental research and public health · 2020Article
- A Review of Oxytocin and Arginine-Vasopressin Receptors and Their Modulation of Autism Spectrum Disorder.Frontiers in molecular neuroscience · 2018Review
- Maladaptive Behavior and Gastrointestinal Disorders in Children with Autism Spectrum Disorder.Pediatric gastroenterology, hepatology & nutrition · 2015Article
- Immune dysregulation in autism spectrum disorder.European journal of pediatrics · 2014Review
- Article
- Use of Complementary and Alternative Medicine in Children with Autism Spectrum Disorders: A Multicenter Study.Noro psikiyatri arsivi · 2013Article
- Autism as the Early Closure of a Neuroplastic Critical Period Normally Seen in Adolescence.Biological systems, open access · 2013Article
- The medical care of children with autism.European journal of pediatrics · 2012Review
- Ferritin and iron levels in children with autistic disorder.European journal of pediatrics · 2012Article
- Using perceptual signatures to define and dissociate condition-specific neural etiology: autism and fragile X syndrome as model conditions.Journal of autism and developmental disorders · 2010Article
- Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder.European child & adolescent psychiatry · 2010Review
- Autism and X-linked hypophosphatemia: A possible association?Indian journal of human genetics · 2010Article
- The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases.Molecular psychiatry · 2009Article
- A 15q13.3 microdeletion segregating with autism.European journal of human genetics : EJHG · 2009Article
- Peripheral biomarkers in Autism: secreted amyloid precursor protein-alpha as a probable key player in early diagnosis.International journal of clinical and experimental medicine · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review on autism spectrum disorder (ASD) focusses on recent insights in the clinical picture, such as continuity of the phenotype and the concept of broader phenotype, on epidemiology and on clinical issues relevant to physicians, including new methods for early screening and diagnosis, psychiatric and somatic co-morbidity, and the expansion of so-called complementary and alternative treatments. ASD is a disorder with mainly genetic causes and recent insights show that a variety of genetic mechanisms may be involved, i.e. single gene disorders, copy number variations and polygenic mechanisms. Technological advances in genetics have lead to a number of promising findings, which, together with other lines of fundamental research, suggest that ASD may be a disorder of connectivity in the brain, at least in a subgroup of patients. It is possible that part of the genetic load in autism actually reflects gene-environment interaction, but there is no evidence for purely environmental causes in a substantial number of cases. Clinical research suggests that ASD may be a multi-system disorder in at least a subgroup of subjects, affecting the gastro-intestinal (GI) tract, the immune system and perhaps other systems. Behavioural treatments remain the cornerstone of management, and are mainly aimed at stimulation of the domains of impaired development and reducing secondary behaviours. These treatments are constantly being refined, but the main progress in this area may be the increase of research on effectiveness.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.