ReviewThe New England journal of medicine2008
Effect of in utero and early-life conditions on adult health and disease.
4 registry-linked trialsAbstract readReview
In one paragraph
Review in The New England journal of medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 1,668 papers, 11 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
1,668citing papers in PubMed, 11 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Is There An Association Between Vitamin D Levels And Insulin Resistance In Polycystic Ovary Syndrome?
The Role of Epigenetics in the Vicious Cycle of Diabetes and Pregnancy (VICYDIP)
The Effect of Early Screening and Intervention for Gestational Diabetes Mellitus on Pregnancy Outcomes: the TESGO Randomized Trial
NCT06509776 enrolling by invitationnot on this mapstarted 2024, after this paper: background citation
Early Life Determinants of Skeletal Maturation and Endocrine Health in Young Adults - A Nationwide Birth Cohort Study
Who cites it
1,668 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Impact of Maternal Underweight on Infant and Maternal Outcomes in Japanese Women: A Systematic Review and Meta-analysis.Journal of epidemiology · 2026Pooled it
- Placental hormones, IGF-1, and early-life growth: endocrine links between birth size and infant metabolic programming-a systematic review.European journal of pediatrics · 2026Pooled it
- Susceptible window identification of the relationship between maternal ozone exposure and preterm birth.International health · 2026Pooled it
- Risk Factors in the First 1000 Days of Life Associated With Childhood Obesity: A Systematic Review and Risk Factor Quality Assessment.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Placental expression and activity of system A and system L amino acid transporters in pregnancies complicated by diabetes mellitus and fetal growth disorders: a systematic review.Frontiers in endocrinology · 2026Pooled it
- Energy intake and physical activity over the course of pregnancy and gestational weight gain: a systematic review and dose-response meta-analysis of data from randomized controlled lifestyle intervention trials.Nutrition journal · 2025Pooled it
- Parental conditions, modifiable lifestyle factors, and first trimester growth and development: a systematic review.Human reproduction update · 2025Pooled it
- Associations Between Maternal Polychlorinated Biphenyls (PCBs) Exposure from Seafood Consumption during Pregnancy and Lactation and Child Growth: A Systematic Review and Meta-Analysis.Advances in nutrition (Bethesda, Md.) · 2025Pooled it
- Nutritional Management of Low Birth Weight and Preterm Infants in Low- and Low Middle-Income Countries.Neonatology · 2025Pooled it
- The one-carbon metabolism as an underlying pathway for placental DNA methylation - a systematic review.Epigenetics · 2024Pooled it
- Association between early exposure to famine and risk of renal impairment in adulthood: a systematic review and meta-analysis.Nutrition & diabetes · 2024Pooled it
- Vitamin D Deficiency During Pregnancy Is Associated With Greater LDL-C Increase, Elevated β-Hydroxybutyrate and Altered Neonatal Metabolic Markers-A Secondary, Pooled Analysis of the Randomized, Controlled Vitamin D and Lifestyle for Gestational Diabetes Prevention Trial (DALI).Endocrinology, diabetes & metabolism · 2026Trial
- Effects of prenatal early food and micronutrient supplementations on body size and cardiometabolic risk factors in the 15-year-old offspring - the MINIMat randomised trial.The Lancet regional health. Southeast Asia · 2026Article
- Childhood Famine Exposure and Late-Life Edentulism: Evidence From Natural Experiments.Journal of clinical periodontology · 2026Article
- MASLD, diabetes and PMOS across the female life stages.Diabetologia · 2026Review
- Particulate Matter Exposure and Accelerated Cardiovascular Aging: Mechanistic Evidence, Biomarker Integration, and the PACA Framework.Cardiovascular toxicology · 2026Review
- Age-dependent effects of aerobic training on cardiac expression of Akt1, mTOR, and CITED4 in immature, young-adult, and middle-aged rat myocardium.European journal of applied physiology · 2026Article
- The role of epigenetic signatures in type 2 diabetes: therapeutic advances and lifestyle interventions.Acta diabetologica · 2026Review
- Maternal autoimmune diseases during pregnancy and mortality up to young adulthood in offspring: a register-based cohort study.EClinicalMedicine · 2026Article
- Developmental Environmental Chronotoxicity by Polystyrene Nanoplastics Exacerbates High-Fat Diet-Induced Pediatric MAFLD Through Circadian Disruption and Mitochondrial Dysfunction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
1,608 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
Authors and funding
4 authors.
Peter D GluckmanLiggins Institute, University of Auckland, and National Research Centre for Growth and Development, Auckland, New Zealand. pd.gluckman@auckland.ac.nz
Mark A Hanson
Cyrus Cooper
Kent L Thornburg
Funding
ULTRASOUND IMAGING COREP01HD034430 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI THOMAS, GEORGE VICTOR · 1997 to 2017
$20.7MArthritis Research UKBritish Heart FoundationMedical Research CouncilNICHD NIH HHS P01 HD034430NICHD NIH HHS P01 HD34430
Abstract
PubMed holds no abstract for this paper.
Indexed as
Epigenesis, GeneticFetal DevelopmentPrenatal Exposure Delayed EffectsPrenatal Nutritional Physiological PhenomenaAdaptation, BiologicalAdultBirth WeightDiseaseFemaleGene Expression RegulationGrowthHealthHumansInfantInfant, NewbornMale
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
NCT02803476ClinicalTrials.gov
NCT03388723ClinicalTrials.gov
NCT03523143ClinicalTrials.gov
NCT06509776ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.