Evidence map›Paper›PMID 18595902›Full record

ArticleBMJ (Clinical research ed.)2008

Secular decline in mortality from coronary heart disease in adults with diabetes mellitus: cohort study.

Ane Cecilie Dale, Lars J Vatten, Tom Ivar Nilsen, Kristian Midthjell, Rune Wiseth

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in BMJ (Clinical research ed.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ane Cecilie DaleDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology. ane.c.dale@ntnu.no
Lars J Vatten
Tom Ivar Nilsen
Kristian Midthjell
Rune Wiseth
Norwegian University of Science and Technology · NOCentre International de Recherche sur le Cancer · FRSt Olav's University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine trends in fatal coronary heart disease in adults with and without diabetes.

designCohort study.

settingTwo surveys of the Nord-Trøndelag health study (HUNT), a population based study in Norway.

participants74 914 men and women from the first survey (1984-6) and 64 829 from the second survey (1995-7).

main outcome measureAge specific mortality from coronary heart disease among adults with and without diabetes during two consecutive nine year follow-up periods.

resultsA total of 2623 men and 1583 women died from coronary heart disease. Mortality rates were substantially lower during the most recent follow-up period: among men aged 70-79 without diabetes, deaths per 1000 person years declined from 16.38 to 8.79 (reduction 48%, 95% confidence interval 39% to 55%) and among women aged 70-79 from 6.84 to 2.68 (62%, 52% to 70%). Among the same age group with diabetes, deaths per 1000 person years in men declined from 38.97 to 17.89 (54%, 32% to 69%) and in women from 28.15 to 11.83 (59%, 37% to 73%). The reduction was more noticeable in age groups younger than 70 at baseline, and less pronounced among people aged 80 or more. Mortality from coronary heart disease was more than twofold higher in people with than without diabetes, with a slightly stronger association in women. The difference in mortality by diabetes status remained almost unchanged from the first to the second survey.

conclusionThe strong general reduction in mortality rates from coronary heart disease from the first to the second follow-up period also benefited people with diabetes, but the more than twofold higher mortality from coronary heart disease associated with diabetes persisted over time.

Indexed as

AgedAged, 80 and overCoronary DiseaseDiabetic AngiopathiesEpidemiologic MethodsFemaleHumansMaleMortalityNorway

Identifiers

PMID18595902
PMCPMC2453302
OpenAlexW2027610820

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.