ArticleInternational journal of colorectal disease2008
Diverticulosis and diverticulitis form no risk for polyps and colorectal neoplasia in 4,241 colonoscopies.
Article in International journal of colorectal disease, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Colonoscopy after CT diagnosis of diverticulitis to exclude colon cancer: a systematic literature review.Radiology · 2012Pooled it
- [Do patients with diverticula have a higher risk of developing polyps and colorectal cancer? Study in a spanish population].Revista espanola de salud publica · 2025Article
- The association between colonic diverticulosis and colorectal polyps in a retrospective cohort study.International journal of colorectal disease · 2025Article
- A multicentre study assessing the role of routine colonoscopy after acute uncomplicated diverticulitis and the incidence of colorectal cancer diagnosis.International journal of colorectal disease · 2023Article
- Association between diverticular disease and colorectal cancer: a bidirectional mendelian randomization study.BMC cancer · 2023Article
- The Association between Colorectal Cancer and Colonoscopic Conditions in Saudi Patients: A 10-Year Cross-Sectional-Retrospective Study.Ethiopian journal of health sciences · 2022Article
- Yield of Post-Acute Diverticulitis Colonoscopy for Ruling Out Colorectal Cancer.Techniques and innovations in gastrointestinal endoscopy · 2022Article
- Impact of periampullary diverticulum on biliary cannulation and ERCP outcomes: a single-center experience.Surgical endoscopy · 2021Article
- Association of Colonic Diverticula with Colorectal Adenomas and Cancer.Medicina (Kaunas, Lithuania) · 2021Article
- Solitary rectal ulcer syndrome in children and adolescents: a descriptive clinicopathologic study.International journal of clinical and experimental pathology · 2021Article
- Colorectal Cancer and Polyps in Diverticulosis Patients: A 10-Year Retrospective Study in 13680 Patients.Gastroenterology research and practice · 2019Article
- Colonic diverticulosis is not a risk factor for colonic adenoma.Therapeutics and clinical risk management · 2018Article
- Low frequency of polyps in colonic regions with diverticulosis.International journal of colorectal disease · 2017Article
- Association between diverticulosis and colonic neoplastic lesions in individuals with a positive faecal immunochemical test.United European gastroenterology journal · 2017Article
- Contemporary Review of Risk-Stratified Management in Acute Uncomplicated and Complicated Diverticulitis.World journal of surgery · 2016Review
- High Probability of an Underlying Colorectal Cancer Among Patients Treated for Acute Diverticulitis. A Population-Based Cohort Follow-Up Study.World journal of surgery · 2016Article
- Risk factors associated with colonic diverticulosis among patients from a defined geographic area.Techniques in coloproctology · 2016Article
- Different Types of Periampullary Duodenal Diverticula Are Associated with Occurrence and Recurrence of Bile Duct Stones: A Case-Control Study from a Chinese Center.Gastroenterology research and practice · 2016Article
- Colonic Diverticula Are Not Associated With an Increased Risk of Colorectal Adenomas.The American journal of gastroenterology · 2015Article
- Colonoscopy after CT-diagnosed acute diverticulitis: Is it really necessary?Canadian journal of surgery. Journal canadien de chirurgie · 2015Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThere are conflicting data concerning the association between diverticular disease and colorectal carcinoma (CRC). This study was performed to determine the prevalence and association of diverticulosis, diverticulitis, polyps, and CRC. MATERIALS AND
methodsIn a cross-sectional, retrospective study, we analyzed the colonoscopy reports of complete colonoscopies and patho-histological results of all patients referred for colonoscopy in a period of 3 months in 18 hospitals in The Netherlands. Diverticulosis was defined as three or more diverticula present and diverticulitis as diverticulosis with inflammation. Polyps were also coded according to localization and size. Advanced neoplastic lesions were defined as polyps >or=10 mm in diameter and/or villous architecture and/or adenomas with high grade dysplasia and/or invasive cancer. Actual and previous described CRC were registered.
resultsA total of 4,241 patients were included in the study [1,996 (47%) male], mean age of 59 and range 18-95. Diverticula, diverticulitis, and polyps were seen in 1,052 (25%), 75 (2%), and 1,282 (30%) patients, respectively. No association was found between patients with polyps and those with and without diverticulosis (p=0.478). Invasive adenocarcinoma and adenomas >or=10 mm were most frequently observed. CRC was present in 372 (9%) patients. Negative relation between diverticulosis and CRC and invasive adenocarcinoma was observed. No association was found between polyps and CRC and patients with diverticulitis and CRC. In conclusion, there is no relation between patients with diverticulosis and higher incidence of polyps or CRC when using age-stratified analysis. No increased risk for polyps or CRC was found in patients with diverticulitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.